Words similar to modulator
Example sentences for: modulator
How can you use “modulator” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, the addition of Tat to PC12 cells up-regulated the expression of the inducible cAMP early repressor (ICER), a specific member of the cAMP-responsive element modulator transcription factor family, in a cAMP-dependent manner.
Interestingly, RSV infection of HEp-2 cells also led to the formation of actin stress fibers and activation of the small cellular GTPase RhoA, a modulator of actin filamentation [ 14 15 16 17 ] . Inhibition of RhoA or its interaction with F resulted in the inhibition of syncytium as well as stress fiber formation and the second cycle of infection [ 14 ] . Recombinant F also activated RhoA in the absence of any other viral protein [ 17 ] . Based on these results, it was inferred that stress fiber formation might be important in some aspects of RSV infection, such as virus spread, elaboration of cytokines from infected cells, and contraction of airway muscles that promotes asthma.
Thus the down-regulation of SNIP1 likely leads to the liberation of CBP/p300 and directly contributes to the well-known transcriptional modulator functions of Smad1 and Smad4.
NO is an important modulator of adhesion molecule expression in both acute and chronic inflammatory states, and may influence the course of IBD.
Activated protein C, an endogenous plasma serine protease with antithrombotic, profibrinolytic and anti-inflammatory properties [ 1 2 3 ] , is an important modulator of the host systemic response to severe infection [ 1 ] . Recently, recombinant human activated protein C (drotrecogin alfa [activated]) was approved for the treatment of adult patients with severe sepsis.
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