Words similar to modulator
Example sentences for: modulator
How can you use “modulator” in a sentence? Here are some example sentences to help you improve your vocabulary:
The ability of Smad1 and Smad4 to target SNIP1 for degradation, thereby freeing CBP/p300 for other transcriptional factors is likely an important mechanism for the transcriptional modulator role of these two Smads.
Activated protein C, an endogenous plasma serine protease with antithrombotic, profibrinolytic and anti-inflammatory properties [ 1 2 3 ] , is an important modulator of the host systemic response to severe infection [ 1 ] . Recently, recombinant human activated protein C (drotrecogin alfa [activated]) was approved for the treatment of adult patients with severe sepsis.
The gel used, as modulator is a soluble mixture of purified type A gelatin from porcine skin and a polysaccharide, type III carrageenan K in nanopure water [ 17 ] . Both components are commercially available for laboratory use (Sigma Chemical Co, St Louis, Mo).
CMV is the most important pathogen among these patients and the virus can cause both direct and indirect effects [ 8 9 10 11 12 13 ] . Among solid organ transplant recipients, the effects of CMV disease are similar among all patients, with the exception being the effect on the transplanted organ [ 10 14 15 16 17 ] . The most common disease presentation of CMV in AIDS patients is retinitis [ 8 11 ] . The significance of CMV disease in transplant and HIV infected individuals goes much further than the direct pathological effects because CMV has been shown to be an immune modulator and may contribute significantly to the net immunosuppressive status of the patient [ 11 ] . This immunomodulation would therefore increase the susceptibility to superinfections from other pathogens.
These data have led to the hypothesis that Btk co-operates with Syk in PLCγ2-dependent BCR signaling and that Btk functions as a signal duration modulator (reviewed in references [ 15, 16]).
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