Words similar to moeb

Example sentences for: moeb

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The crystal structure of the E. coli MoeB-MoaD complex clearly shows the interaction between these two proteins and unambiguously confirms the adenylation role of MoeB [ 7 ] . After a thiocarboxylate moiety is formed on the terminal glycine of each MoaD subunit, the two sulfur atoms are transferred to precursor Z as sulfhydryl groups in a dithiolene configuration.
The functionality of MoeB, MoeBR, and MoeZ are known.
In Ec-MoeB, β sheet 5 (residues 149-155 of Ec-MoeB, Figure 3) forms part of the pocket which accepts the C-terminal portion of MoaD, of which the terminal glycine is subsequently adenylated [ 7 ] . Ec-MoeB I155, located at the C-terminal end of this beta loop, is substituted in MoeBR proteins by Y and in MoeZ proteins by F or Y. These bulky substitutions may restrict access of the C-terminus of MoeD-like proteins and may indicate that a different type of substrate is adenylated by MoeBR and MoeZ.
This dual CXXC motif, found in MoeB, ThiF, and HesA proteins, forms a metal center with a zinc atom [ 7 9 ] . The presence of all four of these cysteines has been shown to be required for activity in MoeB).
In terms of distribution, the MoeB structure (146 sequences) was much more common than the MoeBR structure (12 sequences), while MoeZ was represented by only six sequences in the GenBank non-redundant (nr) database.