Words similar to moeb
Example sentences for: moeb
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The crystal structure of the E. coli MoeB-MoaD complex clearly shows the interaction between these two proteins and unambiguously confirms the adenylation role of MoeB [ 7 ] . After a thiocarboxylate moiety is formed on the terminal glycine of each MoaD subunit, the two sulfur atoms are transferred to precursor Z as sulfhydryl groups in a dithiolene configuration.
MoeB, exemplified by Ec-MoeB, and MoeBR, exemplified by cnxF of Aspergillis nidulans [ 16 ] , participate in the synthesis of MPT-Mo as MSAEs.
All 12 sequences in this region have high similarity to the derived consensus sequence GXGXXG(7X)A(SX)GXGXXG(4X)D(9X)R, which defines a nucleotide binding motif [ 16 25 ] . In addition, all sequences have five residues, or conservative substitutions in the case of Pa-MoeB, shown to participate in the adenylation reaction catalyzed by Ec-MoeB (Figure 3) [ 7 ] . The fact that such high similarities are retained in the ThiF coding region across three bacterial divisions suggests that this domain functions more or less autonomously.
The functionality of MoeB, MoeBR, and MoeZ are known.
There are a number of genomic sequences deposited in GenBank as MoeB proteins, although only a few have been physiologically or genetically proven to function in MPT-Mo synthesis.