Example sentences for: moeb

How can you use “moeb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A similar search using Pa-MoeB as the query yielded 146 sequences with a domain structure similar to MoeB, most of which were entered into the database as MoeB, ThiF, HesA, or ubiquitin-activating enzymes from archaea, bacteria, and eukaryota.

  • Two moeB sequences with evidence for function include a knockout of the open reading frame encoding GenBank accession number BAA35521, which was shown to cause the accumulation of precursor Z in E. coli [ 13 ] and accession number Z95150, which was found to be located within a cluster of other MPT-Mo synthesis genes of Mycobacterium tuberculosis [ 14 ] . MSAEs from eukaryotic organisms have also been characterized: MOCS3 (GenBank accession number NM_014484) from humans and cnx 5 from Arabidopsis thaliana [ 15 ] , respectively, have been sequenced, and cnxF from Aspergillus nidulans [ 16 ] has been both sequenced and physiologically characterized.

  • The crystal structure of the E. coli MoeB-MoaD complex clearly shows the interaction between these two proteins and unambiguously confirms the adenylation role of MoeB [ 7 ] . After a thiocarboxylate moiety is formed on the terminal glycine of each MoaD subunit, the two sulfur atoms are transferred to precursor Z as sulfhydryl groups in a dithiolene configuration.

  • The functionality of MoeB, MoeBR, and MoeZ are known.

  • MoeBR has the ThiF and 2X CXXC domains configured like MoeB but includes an N-terminal rhodanese-like domain, the polyproline motif, and has a Y substitution at position 155 (Ec-MoeB numbering).


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