Words similar to moebr
Example sentences for: moebr
How can you use “moebr” in a sentence? Here are some example sentences to help you improve your vocabulary:
MoeZ has all the components of MoeBR, but all the cysteines in the CXXC motifs are absent and position 155 contains either F or Y. Finally, MoeZdR (MoeZ, deleted Rhodanese) contains the ThiF domain followed by an N-terminal portion of the 2X CXXC domain that has GYRD substituted for the first CXXC and terminates prior to the second CXXC pair.
MoeBR has the ThiF and 2X CXXC domains configured like MoeB but includes an N-terminal rhodanese-like domain, the polyproline motif, and has a Y substitution at position 155 (Ec-MoeB numbering).
Examples of both MoeB ( E. coli ) and MoeBR (CNXF of A. nidulans ) have been characterized as MSAEs, indicating that the C-terminal rhodanese-like domain addition does not inhibit MSAE activity.
We also included Mt-MoeBR because we were interested in the relationships between MoeBR and MoeZ sequences that were coresident in the same genome.
In Ec-MoeB, β sheet 5 (residues 149-155 of Ec-MoeB, Figure 3) forms part of the pocket which accepts the C-terminal portion of MoaD, of which the terminal glycine is subsequently adenylated [ 7 ] . Ec-MoeB I155, located at the C-terminal end of this beta loop, is substituted in MoeBR proteins by Y and in MoeZ proteins by F or Y. These bulky substitutions may restrict access of the C-terminus of MoeD-like proteins and may indicate that a different type of substrate is adenylated by MoeBR and MoeZ.