Words similar to moebr

Example sentences for: moebr

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In Ec-MoeB, β sheet 5 (residues 149-155 of Ec-MoeB, Figure 3) forms part of the pocket which accepts the C-terminal portion of MoaD, of which the terminal glycine is subsequently adenylated [ 7 ] . Ec-MoeB I155, located at the C-terminal end of this beta loop, is substituted in MoeBR proteins by Y and in MoeZ proteins by F or Y. These bulky substitutions may restrict access of the C-terminus of MoeD-like proteins and may indicate that a different type of substrate is adenylated by MoeBR and MoeZ.
In terms of distribution, the MoeB structure (146 sequences) was much more common than the MoeBR structure (12 sequences), while MoeZ was represented by only six sequences in the GenBank non-redundant (nr) database.
Whether sulfur transferase functionality is retained in the rhodanese-like domains of MoeBR and MoeZ and whether these proteins can function to activate a substrate as well as transfer a sulfur-containing moiety is unknown.
MoeBR incorporates a rhodanese-like domain, but MoeB does not.
Indications are that in mycobacteria, MSAE function is performed by MoeBR.