Words similar to modulate
Example sentences for: modulate
How can you use “modulate” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results suggest that D. discoideum cells use a family of related MHCKs to modulate myosin II filament assembly, each with distinct roles.
Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.
To further investigate whether the effect of PMA on CD4 and CD8 expression is consistent with the activation of protein kinase C (PKC), we examined structurally distinct phorbol esters that either have or lack the capacity to activate PKC, for their effectiveness to modulate the levels of CD4 and CD8 mRNAs.
PN-1 and trypsin modulate GnRH neuronal migration in vivo during embryogenesis
ERα enhances AP-1 activity in response to estrogens, [ 28 29 ] but ERβ inhibits AP-1 activity in response to estrogens [ 29 30 31 ] . ERβ also completely suppresses ERα activity at the cyclin D1 promoter and even suppresses the activity of an ERα mutant that is selectively superactive at AP-1 sites and CREs [ 29 ] . Finally, ERβ shows a unique capacity to enhance AP-1 activity in response to selective estrogen receptor modulators (SERMs) such as raloxifene, tamoxifen and ICI 182,780/Faslodex (ICI) [ 30 31 32 ] . Together, these observations suggest that there are fundamental differences in the way that the ERs bind unspecified cofactors that modulate gene expression, and that some of these cofactors must play a role in differential ER activity at AP-1 sites.
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