Words similar to modulate
Example sentences for: modulate
How can you use “modulate” in a sentence? Here are some example sentences to help you improve your vocabulary:
Structurally, the ROCK1 N-terminus contains the protein kinase domain, while the C-terminus has both a Rho-binding domain and a pleckstrin homology domain, either of which can modulate protein–protein interactions.
In addition to the binding sites for natural or endogenous agonists (orthosteric sites), many GPCRs have also been found to have allosteric sites [ 35 ] . These sites can bind natural ligands, as in the case of Zn ions and heparin for the dopamine and neurokinin receptors, respectively, or bind synthetic drugs such gallamine, in the case of the muscarinic receptors [ 35 ] . Binding of small molecules to these allosteric sites can modulate activity of a receptor without directly mimicking or competing out the interaction of ligands to the orthosteric sites.
Although little is known about the physiology and biology of ovarian SC, they have been linked to the genesis of ovary cancer through distinct TGF-β signaling pathways [ 42 43 ] . Significantly, the importance of FS in the genesis of this cancer has been established [ 44 ] . Given the evidence that BMPs are potent growth factors and that FS can modulate their bioactivity, it will be interesting to investigate the possibility that this intrinsic BMP system may be involved to pathogenesis of SC tumors.
Peripheral blood and synovial Tm were than examined in an in vitro culture system in order to determine the relative capacity of differentiation signals to modulate cytokine production.
HDAC inhibitors, such as trichostatin A and trapoxin, modulate gene expression in either a positive, negative or neutral fashion [ 45].
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