Example sentences for: modulators

How can you use “modulators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These putative endogenous Smo modulators could represent orthosteric or allosteric ligands.

  • Photo-Ablatable Lenticular Modulator (PALM) technique refers to the use of a modified collagen gel solution for the photorefractive correction of corneal surface irregularities [ 14 ] . The PALM gel similarly to other collagen modulators [ 12 13 15 ] is thermo reversible.

  • These properties have been met with the use of collagen solutions as modulators.

  • They are structural and functional modulators of extracellular matrices that play important roles in CNS development and repair.

  • ERα enhances AP-1 activity in response to estrogens, [ 28 29 ] but ERβ inhibits AP-1 activity in response to estrogens [ 29 30 31 ] . ERβ also completely suppresses ERα activity at the cyclin D1 promoter and even suppresses the activity of an ERα mutant that is selectively superactive at AP-1 sites and CREs [ 29 ] . Finally, ERβ shows a unique capacity to enhance AP-1 activity in response to selective estrogen receptor modulators (SERMs) such as raloxifene, tamoxifen and ICI 182,780/Faslodex (ICI) [ 30 31 32 ] . Together, these observations suggest that there are fundamental differences in the way that the ERs bind unspecified cofactors that modulate gene expression, and that some of these cofactors must play a role in differential ER activity at AP-1 sites.


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