Example sentences for: modulators

How can you use “modulators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead of independently binding to specific DNA sequence to regulate transcription, Smads are now considered to be transcriptional modulators since their ability to regulate transcription is dependent, in most cases, on their physical interaction with other nearby DNA-binding transcription factors [ 11 ] . Thus, one of the fundamental questions in understanding Smad-regulated transcription is how Smads function as transcription modulators.

  • Masking techniques refer to photorefractive procedures utilizing various masking means or so called modulators to protect flatter corneal areas while steeper areas are excised with the excimer laser.

  • These compounds are potent modulators of pulmonary inflammation and lung injury [ 9].

  • ERα enhances AP-1 activity in response to estrogens, [ 28 29 ] but ERβ inhibits AP-1 activity in response to estrogens [ 29 30 31 ] . ERβ also completely suppresses ERα activity at the cyclin D1 promoter and even suppresses the activity of an ERα mutant that is selectively superactive at AP-1 sites and CREs [ 29 ] . Finally, ERβ shows a unique capacity to enhance AP-1 activity in response to selective estrogen receptor modulators (SERMs) such as raloxifene, tamoxifen and ICI 182,780/Faslodex (ICI) [ 30 31 32 ] . Together, these observations suggest that there are fundamental differences in the way that the ERs bind unspecified cofactors that modulate gene expression, and that some of these cofactors must play a role in differential ER activity at AP-1 sites.

  • Photo-Ablatable Lenticular Modulator (PALM) technique refers to the use of a modified collagen gel solution for the photorefractive correction of corneal surface irregularities [ 14 ] . The PALM gel similarly to other collagen modulators [ 12 13 15 ] is thermo reversible.


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