Words similar to kcnq

Example sentences for: kcnq

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This element, which is ~350 kb distant from Tnfrh1 , is essential in cis for the imprinting of at least 4 genes, Kcnq1 , Cdkn1c , Slc22a1l and Ipl/Tssc3 ( [ 21 22 23 ] and M. Higgins, personal communication).
The neighbor-joining (Figure 3a) and maximum-likelihood trees we constructed, in combination with the fact that mammalian KCNQ1 and Anopheles KCNQ2 gene products share a striking 75% identity (despite the divergence of protostomes and deuterostomes close to 700 million years ago), suggest that gene loss in Drosophila , specifically loss of an ancestral KCNQ2 (mammalian KCNQ1 ), is the cause of this difference, rather than gene expansion in Anopheles , which may be the case for the Kv3 and Irk3 (Figure 3b) gene families.
KCNQ family proteins.
These two elements control, respectively, the allele-specific expression of the H19/Igf2/Ins2 gene cluster, and the second gene cluster containing Kcnq1, the antisense transcript Kcnq1ot1, p57 Kip 2/ Cdkn1c, Slc22a1l, Ipl/Tssc3 and possibly additional genes [ 1 2 ] . There is good evidence assigning one border of the overall imprinted region to the DNA immediately downstream of H19 [ 3 ] . However, the other border, which must lie upstream of Ipl is less well-defined [ 4 ] . Here we show evidence for weak imprinting of a gene, Tnfrh1 , which is located upstream of
Alternatively, lateral transfer of KCNQ1 from mammals to Anopheles must be considered, given the intimate relationship of these organisms.