Example sentences for: kcsa
How can you use “kcsa” in a sentence? Here are some example sentences to help you improve your vocabulary:
Homology models [ 3 4 ] of the M1-P-M2 portion of Kir's have been developed using the backbone structure of KcsA.
The utility of bacterial channels in structural studies has been made abundantly clear by the KcsA structure.
Finally, in our hands homology models based on KcsA developed with Alignment A satisfy the mutagenesis data on which Alignment B is based as do models using alignment B, and models using Alignment A are more consistent with mutagenesis studies of other groups [ 3 13 ] . No single model in which the P segment has the structure of KcsA can satisfy all of the second site suppressor data of Minor et al.
The validity of these models has been challenged by experiments [ 5 ] that were interpreted as indicating that the sequence alignment between KcsA and Kir proposed originally by Doyle et al [ 2 ] for M2 and used in these models is incorrect.
The structural interactions that underlie tetramerization of KcsA on gels are disrupted only by heating the sample and by pH 12 [ 31 ] , treatments that had no effect on the dimerization of VR1 we observed (data not shown).