Example sentences for: kdel

How can you use “kdel” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is possible that in association with another protein or protein complex, the chaperone's KDEL sequence is sterically prevented from binding with ER retention receptors, and this allows the protein to be transported to the plasma membrane.

  • So, for example, in my classes students first read the elegant paper by Munro and Pelham (1987) that uncovered the tetrapeptide lysine–aspartic acid–glutamic acid–leucine (KDEL) retention signal for proteins destined to remain in the endoplasmic reticulum lumen.

  • KDEL, KKXX) have been described on the cell surface in a wide variety of cell types [ 16 17 18 19 20 21 22 23 27 26 28 30 31 ] , though this phenomenon has not been previously described in oocytes or eggs.

  • A number of molecular chaperones are retained in the ER, due to a conserved signal sequence at the C-terminal end of the protein, (KDEL), which binds to a receptor in the Golgi apparatus [ 15 ] . More recently, however molecular chaperones bearing the ER retention signal have been localized to the surface of different cell types.


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