Words similar to heterologous
Example sentences for: heterologous
How can you use “heterologous” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, the N- and C-terminal regions (amino acids 1-171 and 727-927, respectively) of murine NFATp function as activation domains when fused to a heterologous DNA binding domain in transient transfection assays in Jurkat cells [ 28].
We first addressed this issue by transiently transfecting a heterologous promoter containing a consensus AP-1 site fused to the luciferase reporter gene [ 11 ] along with wild type RARα or S77A mutant expression vectors.
This region can, by itself, activate transcription when targeted to the DNA via a heterologous DNA-binding domain [ 5 ] . On the other hand, the LRR plus C-terminal region of yCCR4 cannot mediate transcription activation, but is involved in protein-protein interactions [ 5 ] . The yCCR4 LRR is necessary for the binding of several components of the CCR4-NOT complex, including yPOP2 -and mCAF1- [ 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] , and deletion of the yCCR4 N-terminus does not impair these associations.
Although we have formally demonstrated expression, not replication, our previous demonstration of the replication [ 12 ] of dengue replicons lacking heterologous material suggests that the replicons described here, which contain heterologous material, are indeed replicating.
The frequencies and fluorescence intensities of replicon positive cells seen in the experiments reported here are comparable to those seen for dengue replicons lacking heterologous material [ 12 ] , suggesting that replication of the Δpre-M/E replicons containing heterologous material is occurring as well.
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