Words similar to heterologous
Example sentences for: heterologous
How can you use “heterologous” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results, with the exception of the change in Ca 2+current density, are in remarkable agreement with those obtained when L-type Ca 2+channel subunits are coexpressed without the γ 1 subunit in heterologous cells (see below).
Thus c-crk interacts constitutively with downstream effectors such as C3G via its SH3 domains, and interacts in a phosphotyrosine dependent fashion with tyrosine phosphorylated receptors using its SH2 domain [ 39 ] . To analyze downstream signals regulated by these adaptor proteins, investigators have developed methods that target them to distinct cellular membrane compartments by using heterologous targeting sequences.
The expressed 5-HT 2C receptor exhibits homologous and heterologous desensitization in oocytes [ 32 ] mediated by protein kinase C [ 33 34 35 ] . A calmodulin-dependent kinase may also be involved in homologous desensitization [ 36 ] . In contrast, a recent study indicates that neither PKC nor calmodulin-dependent protein kinase II are involved, instead desensitization of the 5-HT 2C receptor is dependent on GRK activity [ 37 ] . Interestingly, tyrosine kinase involvement in the agonist-mediated phosphorylation of the rat 5-HT 2C receptor has also been reported [ 38 ] , although as yet no report has shown that the 5-HT 2C receptor directly activates tyrosine kinases.
DNA fragments used for desired regions of heterologous genes (see Figure 1) were synthesized by polymerase chain reaction (PCR) from short overlapping primers.
If the unique C-terminal 35 amino acid sequence of sα i2 functions as a Golgi targeting signal, it is important to test whether it is sufficient to target a heterologous protein to intracellular membranes.
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