Words similar to heterologous
Example sentences for: heterologous
How can you use “heterologous” in a sentence? Here are some example sentences to help you improve your vocabulary:
Priming with various types of "live" expression followed by boosting with purified subunits is currently favored as a method to obtain stronger immunologic responses that either method alone [reviewed in [ 1 ] and [ 2 ] ]. Previously acquired immunity to a viral vector such as vaccinia may influence its efficacy in inducing immunity against heterologous proteins being delivered [ 16 17 18 19 ] and it may be wise to provide physicians with HIV vaccines based on a variety of vectors to handle a variety of clinical situations.
This region can, by itself, activate transcription when targeted to the DNA via a heterologous DNA-binding domain [ 5 ] . On the other hand, the LRR plus C-terminal region of yCCR4 cannot mediate transcription activation, but is involved in protein-protein interactions [ 5 ] . The yCCR4 LRR is necessary for the binding of several components of the CCR4-NOT complex, including yPOP2 -and mCAF1- [ 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] , and deletion of the yCCR4 N-terminus does not impair these associations.
In various previous attempts to express heterologous genes in full length, wild type dengue virus, we experienced a very poor success rate, despite attempts to clone heterologous material into various positions of the genome (data not shown).
Each of the probes has been tested for: 1) ability to bind to the receptor, 2) receptor activation in both a heterologous expression system and in native neurons and 3) fluorescence labeling of the receptor.
Upon introduction into a host's cells, these sub-genomic fragments should replicate intracellularly and support prolonged expression of dengue and heterologous immunogens without producing the deleted dengue structural proteins and without forming infectious virions.
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