Example sentences for: heterologous

How can you use “heterologous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether the hypervariable domain of Rab24 was sufficient to promote the formation of inclusion bodies when fused to a heterologous protein, we prepared fusion constructs with enhanced green fluorescent protein (EGFP) containing either full-length Rab24(D123I) or just the Rab24 C-terminal domain.

  • Alternatively, the presence of heterologous Etn element sequences in T Wis transcripts may stimulate posttranscriptional gene silencing by an RNA-induced silencing complex (RISC)-based RNAi degradation pathway which could target degradation of wild type transcripts [ 14 ] .

  • Our finding that dengue virus replicons can express heterologous genes, including HIV envelop, for prolonged periods of time in cell culture without selection represents a significant step in developing a new vector system potentially capable of delivering immunogens to any host in whose cells the dengue replicons can replicate.

  • Thus c-crk interacts constitutively with downstream effectors such as C3G via its SH3 domains, and interacts in a phosphotyrosine dependent fashion with tyrosine phosphorylated receptors using its SH2 domain [ 39 ] . To analyze downstream signals regulated by these adaptor proteins, investigators have developed methods that target them to distinct cellular membrane compartments by using heterologous targeting sequences.

  • Priming with various types of "live" expression followed by boosting with purified subunits is currently favored as a method to obtain stronger immunologic responses that either method alone [reviewed in [ 1 ] and [ 2 ] ]. Previously acquired immunity to a viral vector such as vaccinia may influence its efficacy in inducing immunity against heterologous proteins being delivered [ 16 17 18 19 ] and it may be wise to provide physicians with HIV vaccines based on a variety of vectors to handle a variety of clinical situations.


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