Words similar to heterodimers
Example sentences for: heterodimers
How can you use “heterodimers” in a sentence? Here are some example sentences to help you improve your vocabulary:
PPARs form heterodimers with retinoid X receptor (RXR), and interact with the peroxisome proliferator response element (PPREs) in gene promoters.
The other two types of constructs were heterodimers of A-pocket substitutions with either Y85H or T91I.
Most of these defects are only partially corrected in heterodimers with wild-type or with Y85H and generally are not improved at all in heterodimers with T91I.
This was also the case with the mutants we describe here, all of which formed normal or near normal amounts of capsids in single-chain homodimers and in their heterodimers with wild-type, Y85H and T91I (results not shown).
Studies have shown that the sitosterolemic patients hyperabsorb all sterols (cholesterol and phytosterols) and fail to excrete phytosterols into bile [ 3 4 5 6 7 ] . Positional mapping of the STSL locus to human chromosome 2p21 led to the identification of two genes, ATP binding cassette (ABC) half-transporters G5 and G8 that were mutated in affected individuals [ 8 9 10 11 12 ] . The protein products of these two genes (sterolin-1 and sterolin-2 respectively) are thought to form heterodimers to constitute a functional transporter, based primarily on the genetic evidence that affected individuals are either completely mutated in sterolin-1 or sterolin-2, but not both [ 12 ] . More recently, evidence from in vitro expression of these proteins has been presented that these two proteins co-immunoprecipitate, supporting this conclusion [ 13 ] . ABCG5 and ABCG8 appear to be present in all mammalian genomes examined to date and are highly conserved between species, indicating that these genes may have a similar function in other species.
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