Words similar to heterodimers

Example sentences for: heterodimers

How can you use “heterodimers” in a sentence? Here are some example sentences to help you improve your vocabulary:

The fact that the V29A-Y85H and V29A-T91I heterodimers only partially recover repressor activity, and to about the same extent, indicates that Val29 makes contacts of roughly equal importance at both A-4 and A-10.
Because one binding site remains intact, such mutant-wild-type heterodimers are functional repressors (except in cases where the mutation affects a residue that plays a role in both half-sites).
NAC is an antioxidant thiol that raises the intracellular pool of glutathione the major redox regulating mechanism in the A549 epithelial cell line [ 45 ] . Interestingly, it has been reported that NAC can have differential effects on NF-κB binding activity suggesting only a subset of NF-κB binding complexes are redox sensitive [ 58 ] . Moreover, it has been shown that NAC inhibits Rel A/p50 heterodimers but not p50 homodimers and can inhibit NF-κB binding to only certain variant κB elements which presumably interact with distinct redox sensitive NF-κB binding complexes [ 59 ] . These observations are consistent with our findings that indicate NAC predominantly inhibits Rel A homodimers since that was the major NF-κB subunit induced by RSV infection of A549 cells.
2V29L is also a competent represser, nearly as good as wild-type, as are also the V29L-WT, V29L-Y85H, and V29L-T91I heterodimers.
The p51 subunit with a hexahistidine-tag and a non-tagged p66 were used to generate the heterodimers containing insertion in either or both of the subunits.