Words similar to heterodimers
Example sentences for: heterodimers
How can you use “heterodimers” in a sentence? Here are some example sentences to help you improve your vocabulary:
NAC is an antioxidant thiol that raises the intracellular pool of glutathione the major redox regulating mechanism in the A549 epithelial cell line [ 45 ] . Interestingly, it has been reported that NAC can have differential effects on NF-κB binding activity suggesting only a subset of NF-κB binding complexes are redox sensitive [ 58 ] . Moreover, it has been shown that NAC inhibits Rel A/p50 heterodimers but not p50 homodimers and can inhibit NF-κB binding to only certain variant κB elements which presumably interact with distinct redox sensitive NF-κB binding complexes [ 59 ] . These observations are consistent with our findings that indicate NAC predominantly inhibits Rel A homodimers since that was the major NF-κB subunit induced by RSV infection of A549 cells.
Most of these defects are only partially corrected in heterodimers with wild-type or with Y85H and generally are not improved at all in heterodimers with T91I.
It will be interesting to determine whether Asw homodimers display any binding to Hint substrates, what degree of Hint enzyme activity is retained by the putative Hint-Asw heterodimer, and whether Gln127 is required for depression of Hint enzymatic activity in Hint-Asw heterodimers.
CAR alone, RXR alone, and CAR/RXR heterodimers bound to various ligands were injected individually into flow cells and binding was measured as described [ 25 26 ] .
The JAK/STAT signaling pathway is involved in many cytokines, hormones, and growth factors mediated signaling pathways to regulate a variety of biological responses, including development, cell differentiation, proliferation and survival [ 7 8 ] . Once STAT proteins are activated by tyrosine-phosphorylation, form homo or heterodimers that are translocated to the nucleus, where they can bind to specific sequences in the DNA, thereby stimulating gene transcription.