Example sentences for: heterodimers

How can you use “heterodimers” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This positive response to 9-cis-RA contrasts with the inhibition that would result from the loss of RXR to ligand-dependent homodimers [ 20 ] , confirming that these studies reflect the activity of CAR/RXR heterodimers and demonstrating that such complexes can be permissive for RXR signaling.

  • The rexinoid responsive complexes are referred to as permissive and include the Peroxisome Proliferator Activated Receptor (PPAR) and the Farnesoid X Receptor (FXR) heterodimers; the Retinoic Acid Receptor (RAR), and Thyroid Hormone Receptor (TR) heterodimers are non-permissive [ 2 3 4 5 6 7 ] .

  • Wild-type-mutant heterodimers have a mutation in only one subunit and tell us whether the identity of the mutated A-pocket amino acid is important on only one half of the dimer.

  • The fact that the V29A-Y85H and V29A-T91I heterodimers only partially recover repressor activity, and to about the same extent, indicates that Val29 makes contacts of roughly equal importance at both A-4 and A-10.

  • The proteins with an odd number of EF-hand domains may function as homo- or heterodimers, they may bind Ca 2+in a weaker manner, there may be another 'cryptic' Ca 2+-binding motif that is not identifiable, but is functional, or they may not bind Ca 2+at all.


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