Example sentences for: heteroduplex

How can you use “heteroduplex” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Heterozygotes exhibit an intermediate band that is most likely a heteroduplex DNA fragment.

  • (ii) Mutation of the putative RNAseH active site residues in both Hepatitis B Virus (HBV) and duck hepatitis B virus (DHBV) P blocks synthesis of mature hepadnaviral DNA and results in the expected RNA:DNA heteroduplex [ 19, 21, 22, 23].

  • The two enzymatic active sites of DHBV P are likely to interact with the viral nucleic acids through a single binding interaction because they are very close to each other and because other reverse transcriptases (such as that of HIV) bind to the RNA:DNA heteroduplex as a single protein entity [ 32].

  • Analysis of the DNAs on denaturing gels revealed that the negative polarity DNA synthesized by the D715V mutant was annealed to a complementary strand [ 23], indicating that it was in an RNA:DNA heteroduplex.

  • RNAseH cleaves the RNA strand in a RNA:DNA heteroduplex, but it does not cleave DNA or RNA that is not hybridized to DNA.


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