Words similar to heterodimer

Example sentences for: heterodimer

How can you use “heterodimer” in a sentence? Here are some example sentences to help you improve your vocabulary:

Early during T-cell development in the thymic cortex, thymocytes bear both of the T cell surface glycoproteins CD4 and CD8 and express the α and β heterodimer of the TCR [ 4 ] . Compelling data have demonstrated that CD4 and CD8 molecules participate in the selection of MHC class I or class II restricted T cells in the thymus.
The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.
Of these, one recognized CD63 as reported previously [ 30 ] , and three (including mAb 6B12) recognized a disulfide-linked cell surface heterodimer consisting of an 85 kD heavy chain and a 35 kD light chain.
One might expect a Hint-Asw heterodimer to have substantially less than 50% of the activity of a Hint homodimer if Hint homodimers showed cooperativity with respect to substrate binding and/or hydrolysis.
Strikingly, however, coactivator binding to the heterodimer complex was decreased below the basal level in the presence of both ligands.