Words similar to heterodimer

Example sentences for: heterodimer

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The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.
Recent evidence indicates that the cytokine, leukemia inhibitory factor (LIF) and its functional binding to the high affinity receptor, a heterodimer between low-affinity LIFR and glycoprotein 130 (LIFR:gp130), are players within the HPA cascade of events.
Heterodimer constructs with the K61R mutant already showed that the identity of Lys61 is important in both halves of the dimer [ 4].
In animals, calcineurin is a heterodimer composed of a regulatory B subunit and a protein phosphatase catalytic A subunit.
The third candidate platelet GP gene controls GPIIb/IIIa (integrin α IIb β 3 ), a transmembranous heterodimer with several ligands, including fibrinogen, fibrin, fibronectin, and vWF.