Words similar to heterochromatin
Example sentences for: heterochromatin
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In order to correlate heterochromatin cytology with the genome sequence, we mapped the boundaries of the euchromatin and centric heterochromatin on chromosome arms X, 2L, 2R, 3L and 3R by FISH of BAC-derived probes to mitotic chromosomes (see Materials and methods).
Currently, there are at least two theories regarding the effects of LMNA [ 24 ] . The first postulates that disruptions of the inner nuclear membrane affect heterochromatin scaffolding and thereby gene expression.
Doubtless other regions of the heterochromatin will be represented in large-insert libraries, and BACs will be useful for linking and orienting short WGS3 heterochromatic scaffolds.
In addition to genes required for viability and fertility [ 5], heterochromatin contains essential cis -acting chromosome inheritance loci, including elements required for centromere function [ 6], meiotic pairing [ 7, 8, 9], and sister chromatid cohesion [ 10, 11].
For many years, constitutive heterochromatin was considered to be of little or no functional significance [ 22 ] . This view seemed to be supported by early molecular studies showing that heterochromatin consists almost exclusively of highly repeated and middle repetitive DNA [e.g.
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