Words similar to heterochromatin
Example sentences for: heterochromatin
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Physiological experiments can also be used to characterize heterochromatin-binding proteins [ 45 ] . For example, absence of Swi6 in fission yeast sensitizes cells to thiabendazole (TBZ), a microtubule depolymerizing drug [ 46 ] . Presumably this occurs because absence of Swi6 disrupts centromeric heterochromatin and, as a result, sensitizes cells to drugs that compromise spindle function.
The independence of C/EBPα regulation of proliferation from its intranuclear localization may even be necessary since we have recently determined that pituitary cell differentiation is associated with the dispersal of C/EBPα from peri-centromeric heterochromatin by the pituitary-specific transcription factor Pit-1 (J.
These two genes present an interesting contrast in that one of them, Chitinase 3 (Cht3) , is located within constitutive heterochromatin (Genbank accession: AE002743) while the other, cathD , is located in a euchromatic region of the chromosome (Genbank accession: AE003839).
For example, to analyze the draft sequence of the repeat-rich heterochromatin [ 40], we needed to adjust the parameters and datasets used, but also to develop an entirely new repeat-masking approach to facilitate gene finding in highly repetitive regions.
In addition to genes required for viability and fertility [ 5], heterochromatin contains essential cis -acting chromosome inheritance loci, including elements required for centromere function [ 6], meiotic pairing [ 7, 8, 9], and sister chromatid cohesion [ 10, 11].