Words similar to heteroclitic
- het
- hetauda
- hetero-compound
- heterochromatic
- heterochromatically
- heterochromatin
- heterochromatin-binding
- heterochromatin-derived
- heterochromatin-euchromatin
- heteroclitic
- heterocomplex
- heterocoupling
- heterocycle
- heterocycles
- heterocyst
- heterodera
- heteroderidae
- heterodimer
- heterodimerization
- heterodimers
Example sentences for: heteroclitic
How can you use “heteroclitic” in a sentence? Here are some example sentences to help you improve your vocabulary:
This notion has support from studies in tolerized mice: vaccination with a heteroclitic peptide analog recruited T cells, which were responsive to secondary stimulation with native peptide [41,42].
In summary, we have demonstrated that vaccination with heteroclitic peptide at high concentrations may drive T cell responses of variable tumor-cytolytic potential in cancer patients—and that the ability to lyse tumor cells correlates with the T cell's RE for native peptides.
Therefore, optimized use of heteroclitic peptide to induce an initial peptide-specific T cell response, followed by selective expansion of the highest RE tumor-lytic T cells may be needed for an effective strategy with clear clinical application.
Thus, high doses of peptide and/or the higher levels of expression of heteroclitic peptide on APCs may induce and actively propagate predominantly T cells with RE too low for recognition of physiological levels of the native peptide present on tumor targets.
Moreover, in vitro stimulation of T cells from healthy donors with heteroclitic peptides results in expansion of cells with a wide range of RE [23].