Example sentences for: heteroclitic

How can you use “heteroclitic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consequently, heteroclitic peptide analogs are predicted to be more immunogenic than their native counterparts because of more stable binding at the surface of antigen-presenting cells (APCs).

  • These results emphasize how difficult it is to translate findings, such as the spectacular results obtained by the vaccination of TCR transgenic mice with heteroclitic peptides [12], into an application for normal animals and humans.

  • Peripheral blood mononuclear cell (PBMC) samples were isolated from patients after vaccination with the heteroclitic peptides MART 26–35 (27L) (ELAGIGILTV) and gp100 209–217 (210M) (IMDQVPSFV) at the University of Southern California Norris Cancer Center (Los Angeles, California, United States).

  • Thus, naïve TAA-specific T cells, with inadequate RE to become activated by low densities of native peptides present on tumor cells, may become efficient in tumor lysis upon vaccination with heteroclitic peptide.

  • Importantly, the vaccine-elicited clones also exhibited wide variations in RE even for the heteroclitic peptide, compared to the endogenous responses (Figure 5E and 5F).


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