Words similar to heterodimeric
Example sentences for: heterodimeric
How can you use “heterodimeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
Preparation of the heterodimeric enzyme with subunit specific insertion
Cys→Ser mutation at position 280 in the p51 subunit has been shown to alter the RNase H activity of the heterodimeric enzyme, indicating that this residue in the thumb subdomain of p51 plays an important role in support of the RNase H activity of p66 [ 22 ] . The emergence of a strain of HIV-1 resistant to the non-nucleoside RT inhibitor TSAO (Tertbutyldimethyl silyspiro amino oxathioledioside) displaying Glu→Lys mutation at position 138 in the p51 subunit of HIV-1 RT has also been reported [ 23 ] , thus implicating p51 to play a more direct role in drug binding and/or the enzymatic activities of HIV-1RT.
The amino acid sequences of the Runt domains of all each of the collected genes, together with two previously described sequences from the spider Cupiennius salei [ 15 ] , a sequence from the crayfish Pacifastacus leniusculus , and one from the nematode Meloidogyne hapla , were aligned using Clustal W [ 16 ] , as shown in Figure 2. Functionally, the Runt domain is required both for DNA binding and for interaction with its heterodimeric partner (the beta subunit), which serves to allosterically enhance the DNA binding of the Runt domain [ 1 14 ] . Superposition of the alignment and the known crystal structure of mouse Runx1 [ 14 17 ] reveals that residues that make either direct or indirect contact with DNA are invariant (marked by asterisks in Fig.
Cultured BMPCs were immunostained by antibodies to vimentin, type I collagen, and BMP receptors (heterodimeric structures expressed on mesenchymal lineage cells).
The wild type p51 alone exhibited very low DNA binding affinity with a K d[DNA] 1300-fold higher than the wild type heterodimeric enzyme.
Loading...