Words similar to heterodimeric
Example sentences for: heterodimeric
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The amino acid sequences of the Runt domains of all each of the collected genes, together with two previously described sequences from the spider Cupiennius salei [ 15 ] , a sequence from the crayfish Pacifastacus leniusculus , and one from the nematode Meloidogyne hapla , were aligned using Clustal W [ 16 ] , as shown in Figure 2. Functionally, the Runt domain is required both for DNA binding and for interaction with its heterodimeric partner (the beta subunit), which serves to allosterically enhance the DNA binding of the Runt domain [ 1 14 ] . Superposition of the alignment and the known crystal structure of mouse Runx1 [ 14 17 ] reveals that residues that make either direct or indirect contact with DNA are invariant (marked by asterisks in Fig.
The ligands ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and a novel neurotrophin set, known alternatively as NNT-1/BSF3 and CLF/CLC, also function through the high affinity LIFR:gp130 heterodimeric receptor but require a third ligand-binding but non-signaling subunit [ 1 2 3 4 ] . Oncostatin M (OSM) utilizes LIFR:gp130 as an alternative receptor complex for OSM signaling in humans [ 5 ] , but not in mice [ 6 ] . Thus, in mice LIFR:gp130 is obligatory for signaling induced by LIF, CNTF, CT-1 and CLF/CLC.
Cultured BMPCs were immunostained by antibodies to vimentin, type I collagen, and BMP receptors (heterodimeric structures expressed on mesenchymal lineage cells).
Preparation of the heterodimeric enzyme with subunit specific insertion
The InterPro documentation IPR000308 for 14-3-3 proteins describes them as a large family of proteins that are primarily homo- or heterodimeric within all eukaryotic cells.
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