Words similar to heterodimeric
Example sentences for: heterodimeric
How can you use “heterodimeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
The ligands ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and a novel neurotrophin set, known alternatively as NNT-1/BSF3 and CLF/CLC, also function through the high affinity LIFR:gp130 heterodimeric receptor but require a third ligand-binding but non-signaling subunit [ 1 2 3 4 ] . Oncostatin M (OSM) utilizes LIFR:gp130 as an alternative receptor complex for OSM signaling in humans [ 5 ] , but not in mice [ 6 ] . Thus, in mice LIFR:gp130 is obligatory for signaling induced by LIF, CNTF, CT-1 and CLF/CLC.
Preparation of the heterodimeric enzyme with subunit specific insertion
Cys→Ser mutation at position 280 in the p51 subunit has been shown to alter the RNase H activity of the heterodimeric enzyme, indicating that this residue in the thumb subdomain of p51 plays an important role in support of the RNase H activity of p66 [ 22 ] . The emergence of a strain of HIV-1 resistant to the non-nucleoside RT inhibitor TSAO (Tertbutyldimethyl silyspiro amino oxathioledioside) displaying Glu→Lys mutation at position 138 in the p51 subunit of HIV-1 RT has also been reported [ 23 ] , thus implicating p51 to play a more direct role in drug binding and/or the enzymatic activities of HIV-1RT.
In the transmembrane region, although there is ample evidence for heterodimeric transmembrane domain association (Adair and Yeager 2002; Schneider and Engelman 2003; Gottschalk and Kessler 2004; Luo et al.
Major histocompatibility complex class II molecules (MHCII) are heterodimeric transmembrane glycoproteins that bind antigenic peptides and present such peptides to CD4+ T cells.
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