Words similar to heteromeric
Example sentences for: heteromeric
How can you use “heteromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
For those ion channels within this superfamily for which stoichiometry has been directly examined, all have been shown to be composed of four six-transmembrane domain subunits or pseudosubunits, with auxiliary subunits sometimes present as well [ 22 ] . An initial characterization of VR1 channels expressed in Cos and CHO cells has recently revealed that, under certain conditions, they run as multimers on pseudo-native (PFO) gels, with tetramers being one of the primary bands observed [ 23 ] . Thus, like other six membrane spanning domain channels, VR1 almost certainly forms as a tetramer; whether it combines with homologous subunits to form heteromeric channels remains to be determined.
NMDA receptors are heteromeric ion channels composed of one NR1 subunit with combination of other NR2 subunits [ 4, 5, 6, 7].
Like other members of the TGF-β superfamily, BMPs induce intracellular signaling via heteromeric complexes of the type I and type II serine-threonine kinase receptors [ 5 6 ] . The Smad family proteins are now known to function as key signal transducers downstream of the TGF-β family type I receptors [ 6 7 8 ] . The activated BMP type I receptors directly recruit and phosphorylate a set of cytoplasmic Smad proteins that are specific for the BMP type I receptors.
When coexpressed with VR1, heteromeric channels composed of both types of subunits are expected to form.
If the higher molecular weight band does represent a dimer of subunits, the heteromeric VR1/Δ2-52 ought to be intermediate in size between the homomeric dimers.
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