Example sentences for: heteromeric

How can you use “heteromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NMDA receptors are heteromeric ion channels composed of one NR1 subunit with combination of other NR2 subunits [ 4, 5, 6, 7].

  • If the higher molecular weight band does represent a dimer of subunits, the heteromeric VR1/Δ2-52 ought to be intermediate in size between the homomeric dimers.

  • When coexpressed with VR1, heteromeric channels composed of both types of subunits are expected to form.

  • TGFβ signals through a heteromeric receptor complex of type II and type I receptor serine-threonine kinases, which activates the downstream Smad signal transduction pathway [ 7 ] . After TGFβ binding to the receptor complex, the TGFβ type II receptor kinase phosphorylates TGFβ type I receptor which inititates the downstream response by phosphorylating receptor-regulated Smads (R-Smads), such as Smad2 and Smad3.

  • Like other members of the TGF-β superfamily, BMPs induce intracellular signaling via heteromeric complexes of the type I and type II serine-threonine kinase receptors [ 5 6 ] . The Smad family proteins are now known to function as key signal transducers downstream of the TGF-β family type I receptors [ 6 7 8 ] . The activated BMP type I receptors directly recruit and phosphorylate a set of cytoplasmic Smad proteins that are specific for the BMP type I receptors.


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