Example sentences for: heteromeric

How can you use “heteromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • When coexpressed with VR1, heteromeric channels composed of both types of subunits are expected to form.

  • BMPs interact with target cells through a heteromeric complex of type I and type II transmembrane receptors, coupled to an intracellular downstream pathway that includes Smad transcription factors.

  • Like other members of the TGF-β superfamily, BMPs induce intracellular signaling via heteromeric complexes of the type I and type II serine-threonine kinase receptors [ 5 6 ] . The Smad family proteins are now known to function as key signal transducers downstream of the TGF-β family type I receptors [ 6 7 8 ] . The activated BMP type I receptors directly recruit and phosphorylate a set of cytoplasmic Smad proteins that are specific for the BMP type I receptors.

  • In most cells, unliganded glucocorticoid receptors (GR) reside predominately in the cytoplasm, where they exist as a heteromeric complex comprised minimally of GR, 90-kDa and 70-kDa heat shock proteins (hsp90 and hsp70).

  • Based on data obtained from affinity labeling and site directed mutagenesis studies, several regions of the nicotinic acetylcholine receptor have been implicated in ligand binding [ 10 ] . Six essential loops appear to contribute to the binding site with the position of each loop differing slightly depending on whether the receptor is heteromeric or homomeric [ 4 ] . For homomeric receptors such as the α7 nAChR, the loops are identified as A, B, C, D, E and F [ 4 11 ] . The amino acids that interact with ligands presumably extend into the binding site from these loops.


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