Example sentences for: heteromeric

How can you use “heteromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If the higher molecular weight band does represent a dimer of subunits, the heteromeric VR1/Δ2-52 ought to be intermediate in size between the homomeric dimers.

  • BMPs interact with target cells through a heteromeric complex of type I and type II transmembrane receptors, coupled to an intracellular downstream pathway that includes Smad transcription factors.

  • Like other members of the TGF-β superfamily, BMPs induce intracellular signaling via heteromeric complexes of the type I and type II serine-threonine kinase receptors [ 5 6 ] . The Smad family proteins are now known to function as key signal transducers downstream of the TGF-β family type I receptors [ 6 7 8 ] . The activated BMP type I receptors directly recruit and phosphorylate a set of cytoplasmic Smad proteins that are specific for the BMP type I receptors.

  • In most cells, unliganded glucocorticoid receptors (GR) reside predominately in the cytoplasm, where they exist as a heteromeric complex comprised minimally of GR, 90-kDa and 70-kDa heat shock proteins (hsp90 and hsp70).

  • Two splice variants of an A subunit (long and short forms), and a single B subunit have been cloned [ 10 11 12 13 ] . Both the long and short forms of the A subunit are capable of forming functional homomeric receptors [5-HT 3AL R and 5-HT 3AS R] although some differences between an agonist and partial agonist activity have been observed [ 14 ] . A third subtype is formed by a combination of the A and B subunits to produce a heteromeric receptor of unknown stoichiometry [ 10 ] . Heteromeric receptors are pharmacologically and functionally distinct from the homomeric 5-HT 3AL and 5-HT 3AS receptors [ 11 ] .


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