Words similar to heteromeric
Example sentences for: heteromeric
How can you use “heteromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
When coexpressed with VR1, heteromeric channels composed of both types of subunits are expected to form.
For those ion channels within this superfamily for which stoichiometry has been directly examined, all have been shown to be composed of four six-transmembrane domain subunits or pseudosubunits, with auxiliary subunits sometimes present as well [ 22 ] . An initial characterization of VR1 channels expressed in Cos and CHO cells has recently revealed that, under certain conditions, they run as multimers on pseudo-native (PFO) gels, with tetramers being one of the primary bands observed [ 23 ] . Thus, like other six membrane spanning domain channels, VR1 almost certainly forms as a tetramer; whether it combines with homologous subunits to form heteromeric channels remains to be determined.
NMDA receptors are heteromeric ion channels composed of one NR1 subunit with combination of other NR2 subunits [ 4, 5, 6, 7].
Two splice variants of an A subunit (long and short forms), and a single B subunit have been cloned [ 10 11 12 13 ] . Both the long and short forms of the A subunit are capable of forming functional homomeric receptors [5-HT 3AL R and 5-HT 3AS R] although some differences between an agonist and partial agonist activity have been observed [ 14 ] . A third subtype is formed by a combination of the A and B subunits to produce a heteromeric receptor of unknown stoichiometry [ 10 ] . Heteromeric receptors are pharmacologically and functionally distinct from the homomeric 5-HT 3AL and 5-HT 3AS receptors [ 11 ] .
BMPs interact with target cells through a heteromeric complex of type I and type II transmembrane receptors, coupled to an intracellular downstream pathway that includes Smad transcription factors.
Loading...