Words similar to heterotrimeric
Example sentences for: heterotrimeric
How can you use “heterotrimeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our model does differ in several respects from the canonical pheromone response pathway depicted in Fig 1. It includes more members of the heterotrimeric G protein complex, including the alpha, beta, and gamma subunits, the GDP-GTP exchange factor, and the GTPase-activating protein (Gpa1p, Ste4p, Ste18p, Cdc24p, and Sst2p, respectively).
Signaling by the IGF-IR has been studied in many different cell types and is important for proliferation, survival, motility, adhesion, transformation, tumor formation and metastasis [for reviews see refs [ 31 32 ] ]. The receptor can directly phosphorylate the insulin receptor substrate 1 (IRS-1) and Shc proteins in the intact cell causing activation of PI-3Kinase and ras signaling [ 33 ] . More recently, it has been shown that the IGF-IR signals via the Gβγ subunits of the heterotrimeric Gi complex to stimulate PI-3Kinase and ras, and also activates the JAK/Stat pathway to cause phosphorylation of Stat3 [ 34 35 ] .
Bitter stimuli bind to T2R/TRB taste receptors coupled to a heterotrimeric G protein complex consisting of α-gustducin and its partners, β3 and γ13.
Kinesin-interacting protein KAP3 that has armadillo repeats is thought to mediate cargo binding as part of a heterotrimeric complex with two kinesins in the KRP85/95 subfamily [ 18].
In addition to their well characterized role at the PM in coupling activated GPCRs to effector proteins, heterotrimeric G proteins have been implicated in a variety of other cellular functions, including membrane trafficking pathways.
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