Example sentences for: heterozygote

How can you use “heterozygote” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Specifically, population heterozygote advantage may be observed when resistance is additive (heterozygotes have risks equal to the average of the risks of the corresponding homozygotes), when resistance is recessive, or even when it is underdominant (heterozygotes have higher risk of disease than either corresponding homozygote).

  • In this situation, population heterozygote advantage does not require overdominance, but merely allele effects that are more than additive (partial dominance).

  • The catalytic domains are similar to one another (41% amino acid identity) indicating that they have arisen by duplication and divergence [ 22 ] . One estimate indicated a 2% mutant heterozygote frequency in European Americans [ 23 ] but, given the rarity of diagnosed SI deficiency, this seems high.

  • Simple and accurate methods exist to determine for a single pair of alleles how the three possible genotypes (2 homozygotes and one heterozygote) affect disease outcome, and these methods have been used frequently in the literature on autoimmunity and HLA [ 28 29 30 ] and once (to our knowledge) in the HLA-infectious disease literature [ 33 ] . It is of additional interest for epidemiologists, immunologists, vaccine designers and evaluators, and population geneticists to know whether HLA heterozygosity in general improves the immune response to and outcome of infectious diseases.

  • However, if only one of the two reactions fail in a two reaction/ single allele per well format, a heterozygote could be miscalled as a homozygote.


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