Example sentences for: heterozygote

How can you use “heterozygote” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These were embryonic lethals, but when we looked at heterozygote carriers of these mutations, some developed cancer at a high rate as adults’.

  • Figure 1shows the parameter regions in which population heterozygote advantage is expected and those in which the contrary is expected: homozygotes on average are more likely to have a favorable disease course.

  • Of the two ways described above in which MHC genotype may affect disease outcome, the first - association between a particular allele and disease outcome - has been repeatedly documented in human populations by various methods of genetic epidemiology [ 17 ] . The second kind of effect, more vigorous immune responses to a pathogen by a heterozygote as compared to homozygotes for the same alleles, which we term "allele-specific overdominance," has been suggested by several animal studies [ 18 19 20 21 ] , although none of these studies is unambiguous (see DISCUSSION).

  • In contrast, we have shown that population heterozygote advantage depends on not only the effects of individual genotypes on disease outcome, but also on allele frequencies.

  • Meanwhile, findings of population heterozygote advantage should not be interpreted as confirming the mechanism of allele-specific overdominance.


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