Example sentences for: heterologously

How can you use “heterologously” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In support of this model it has been found that the kinetics of ATP-induced pore formation in HEK cells, heterologously expressing the P2X 7 receptor, appears to depend on molecular size of the permeating ionic species [ 19].

  • To assess the role of Siah1a binding, specific group I mGluRs were heterologously expressed in sympathetic neurons from the rat superior cervical ganglion (SCG), which do not natively express mGluRs [ 37 38 ] . The functional role of Siah1a was assessed by examining calcium current inhibition mediated by the expressed mGluRs in the absence and presence of heterologous Siah1a expression.

  • In this case, it must be assumed that under control conditions (cells heterologously expressing only the receptors), mGluRs associate with natively-expressed CaM.

  • When Siah1a is caused to express heterologously (at presumably high levels) it expresses at levels high enough to out-compete native CaM for mGluR binding.

  • 4-aminopyridine, at millimolar concentrations, completely inhibits K +currents conducted by heterologously expressed KCNA channels and native GC I Kur , but lacks significant effects on native GC I Ks [ 4 12 13 20 ] . Kusaka showed that antagonism of 4-AP sensitive slowly inactivating delayed rectifier K +currents suppressed both basal and luteinizing hormone (LH)-stimulated progesterone production [ 21 ] . In this report, we extend those findings by demonstrating 4-AP inhibition of follicle stimulating hormone (FSH)-stimulated progesterone production, and by elucidating the underlying mechanisms.


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