Words similar to hepatocyte
Example sentences for: hepatocyte
How can you use “hepatocyte” in a sentence? Here are some example sentences to help you improve your vocabulary:
Chess and coworkers have shown that transforming growth factor-α and hepatocyte growth factor increase the phosphorylation of p44/p42 MAPK in H441 cells [ 23 ] . Epidermal growth factor, which binds to the same receptor as transforming growth factor-α, increases SP-A content in human fetal lung [ 24 ] . Hepatocyte growth factor has also been shown to upregulate the synthesis of SP-A in rat type II cells [ 25 ] . Thus, phosphorylation of p44/42 MAPK may be involved in the up-regulation of SP-A gene expression, results consistent with our observation that inhibition of basal levels of p44/42 MAPK phosphorylation may decrease SP-A gene expression.
Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine factor produced primarily by mesenchymal cells.
To date, the genes that have been shown to be responsive to regulation by FXR encode proteins involved in the biosynthesis and transport of bile acids [ 13 ] . Bile acids have been shown to modulate a variety of other cellular functions, such as secretion of lipoproteins from hepatocytes [ 14 15 ] and translocation of bile acid transporters to the hepatocyte canalicular membrane [ 16 ] . In McNtcp cells, which are liver-derived cells engineered to transport bile acids actively [ 17 ] , taurine-conjugated bile acids induce the formation of intracellular vesicles that resembles structures observed in cholestatic liver cells without apparent cellular cytotoxicity [ 1 18 ] . In contrast, glycine-conjugated bile acids promote apoptosis in these cells [ 19 ] . Thus, different classes of conjugated bile acids stimulate distinctive responses in McNtcp cells.
The system used in this study was validated for the detection of basic tissue elements including hepatocyte nuclei, other nuclei, vacuoles and sinusoids.
It is estimated that the liver of a 350 g rat contains about 1.8 10 9hepatocytes [ 10 ] . Thus the average number of infectious units per hepatocyte is about 1.5.
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