Words similar to hepatocytes
Example sentences for: hepatocytes
How can you use “hepatocytes” in a sentence? Here are some example sentences to help you improve your vocabulary:
To date, the genes that have been shown to be responsive to regulation by FXR encode proteins involved in the biosynthesis and transport of bile acids [ 13 ] . Bile acids have been shown to modulate a variety of other cellular functions, such as secretion of lipoproteins from hepatocytes [ 14 15 ] and translocation of bile acid transporters to the hepatocyte canalicular membrane [ 16 ] . In McNtcp cells, which are liver-derived cells engineered to transport bile acids actively [ 17 ] , taurine-conjugated bile acids induce the formation of intracellular vesicles that resembles structures observed in cholestatic liver cells without apparent cellular cytotoxicity [ 1 18 ] . In contrast, glycine-conjugated bile acids promote apoptosis in these cells [ 19 ] . Thus, different classes of conjugated bile acids stimulate distinctive responses in McNtcp cells.
Still the number of infectious particles per hepatocytes might be higher in the Brown Norway rats.
It has been shown that hepatocytes exposed to 100 mM ethanol for 16 hr have a higher activity of p38MAPK induced by EGF treatment [ 41 ] . If in our experiments PMA did act through Ser727 phosphorylation of STAT1, the potentiating effect of ethanol can possibly be explained by its ability to stimulate the MAPK kinase cascade.
To explore whether differences in the number of transduced hepatocytes could account for the observed differences in transgene expression levels, we injected different doses (10 9iu, 3.10 9iu and 10 10iu) of Ad5 Adapt LacZ into the tail vein of the rats.
In Fas deficient hepatocytes, toxic bile acids were still able to induce apoptosis, suggesting that bile acids are capable of stimulating multiple pathways to initiate cell death [ 26 ] .
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