Example sentences for: hepatocellular

How can you use “hepatocellular” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 53 ] We propose that drugs that are known to cause hepatocellular injury and also to be thyroid hormone antagonists should be absolutely contraindicated in mefloquine users; such drugs include amiodarone, benzodiazepines, calcium channel blockers and phenytoin.

  • Unlike most other viral hepatitis infections that tend to be acute, hepatitis C infections are often chronic and persist for decades [ 1 2 3 ] . The long-term sequelae of chronic HCV infections include increased risks of liver cirrhosis and hepatocellular carcinoma [ 4 5 ] .

  • [ 6 ] demonstrated that in patients chronically infected with hepatitis B and/or hepatitis C viruses, the M6P/IGF2R is mutated not only in hepatocellular carcinomas (HCCs), but also in the phenotypically normal hepatocytes adjacent to these tumors.

  • Phyllanthus urinaria plant was used by Caribs with other plants in a bath against bad luck (called 'piai') [ 66 ] . Pharmacological activities of various compounds in some species of Phyllanthus include analgesic, antiinflammatory, antilipoxigenase, antiallergic, nitrosamina blocker, aldose reductase inhibitor, antiviral, mitochondrial ATPase inhibitor, phosphodiesterase inhibitor and cyclooxigenase inhibitor [ 111 ] . Other activities are hepatoprotective, phosphorilase and tirosine kinase inhibitor, phospholipase A 2 inhibitor and increased the survival of hepatocellular carcinoma harbouring animals [ 54 111 113 112 ] . The compound with hepatoprotective activity is triacontanol [ 114 ] . Several compounds found in Phyllanthus species, like flavonoids (quercetin, rutin), tannins (geraniin, furosin), benzenoids (ethyl gallate, methyl gallate) and phytosterols showed antinociceptive effects in mice or multiple mechanisms of action [ 111 115 ] . The flavonoids also have anti-inflammatory properties [ 38 11 ] . The hydroalcoholic extracts of four Phyllanthus species were 2 - 6 fold more active in causing antinociception than aspirin depending on the route of administration and the pain model used [ 115 ] . Phyllanthus amarus has antioxidant properties, reverses chromosomal alterations induced by genotoxic agents and has anticancer activity [ 112 ] . Active compounds may be flavonoids (quercetin, astragalin), ellagitannins (amarinic acid), hydrolysable tannins (phyllanthisiin D) [ 112 ] . The multiple plant compounds found in Phyllanthus species might help clear up any physiological condition that results in dogs having difficulty following game animals.

  • • Our findings suggest that cholestasis in preterm infants receiving TPN is induced, in large part, by mechanisms that are not dependent on oxidant-mediated hepatocellular injury


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