Words similar to hepatic
Example sentences for: hepatic
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Purified E-FABP has five fold higher affinity for 18:0, than for 18:1n9 and 20:4n6 (22:6n3 not studied) [ 69 ] . Herein, hepatic E-FABP expression (Fabp5 transcript) was down regulated by all three diets (-5.
Cyclooxygenase activity was assessed ex vivo in hepatic tissue following a previously described method [ 30 ] . Briefly, mice were euthanized 3 hours following the final dose of vehicle or aspirin and a sample of liver tissue (~100 mg) was obtained.
Other mechanisms that may participate in the RU 486-induced inhibition of hepatic apoptosis include the fact that this compound blocks the inhibitory effect of glucocorticoids on suppressors of cytokine signalling in the liver [ 8 ] . This family of proteins is induced by growth hormones and cytokines, and is strongly repressed in vivo by glucocorticoids [ 8 ] . Up-regulation of these proteins by RU 486 [ 8 ] , coupled with significant increase in hepatic TNFα level found in animals treated with RU 486 [ 12 ] , may contribute to the inhibition of apoptosis observed in our study (Fig 1B).
Feeding of all three LC-PUFA diets led to an increase in hepatic Pck1 transcription, indicating gluconeogenesis was favored over glycolysis.
Nine hepatic cytochrome p450 family members were differentially regulated by LC-PUFA (Cyp1a2, Cyp2a4, Cyp2b9, Cyp3a11, Cyp3a16, Cyp4a10, Cyp4a14, Cypf13, and Por).