Words similar to heparan
Example sentences for: heparan
How can you use “heparan” in a sentence? Here are some example sentences to help you improve your vocabulary:
RASMC HSPGs were analyzed further by immunoblotting with the monoclonal antibody 3G10 which specifically recognizes desaturated uronates on the heparan sulfate stubs that remain associated with core proteins after heparitinase digestion [ 37 ] . Complete digestion of RASMC lysates with heparitinase reveals major bands at 46 kDa and 70 kDa, indicating that these are the sizes of the major HSPG core proteins (not shown).
GPC5 belongs to the cell surface heparan sulfate proteoglycan family and is expressed in limb, kidney, developing central nervous system and brain tissue [ 21 22 ] . In vertebrates 6 glypican family members belonging to the proteoglycan family have so far been characterized [ 23 ] . Although there is a high degree of conservation of polypeptide sequence among family members, they are localized to different chromosomes.
The data suggest that heparan sulfate participates in the formation of a PEDF binding complex with its cell-surface receptor, and constitutes a positive modulator for the PEDF-receptor interactions.
At the epithelium, GnRH neurons cross the basal laminae to initiate their migratory phase [ 15 ] . The olfactory nerve expresses several matrix molecules [heparan and keratan sulfate proteoglycans [ 26 ] , laminin [ 27 ] , phosphocan [ 28 ] , lectin-binding domains [ 29 ] ]. Any or all of these may serve as substrates for proteolysis.
The amino acid sequence of the heparin-binding region of HB-EGF ( 21KRKKKGKGLGKKRDPCLRKYK 41) [ 2 ] has been shown to have a strong affinity for heparin and may influence the interaction of this growth factor with cell-surface negatively charged heparan sulfate proteoglycans [ 22 ] . It remains to be seen whether specific/all of the EGF-like modules are required and whether calcium is needed for the interaction of HB-EGF with LTBP-3.
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