Words similar to heparan
Example sentences for: heparan
How can you use “heparan” in a sentence? Here are some example sentences to help you improve your vocabulary:
The results presented above indicate that a heparan sulfate proteoglycan (HSPG) or dermatan sulfate proteoglycan on the surface of RASMCs may serve as a receptor for III1-C.
At the epithelium, GnRH neurons cross the basal laminae to initiate their migratory phase [ 15 ] . The olfactory nerve expresses several matrix molecules [heparan and keratan sulfate proteoglycans [ 26 ] , laminin [ 27 ] , phosphocan [ 28 ] , lectin-binding domains [ 29 ] ]. Any or all of these may serve as substrates for proteolysis.
GPC5 belongs to the cell surface heparan sulfate proteoglycan family and is expressed in limb, kidney, developing central nervous system and brain tissue [ 21 22 ] . In vertebrates 6 glypican family members belonging to the proteoglycan family have so far been characterized [ 23 ] . Although there is a high degree of conservation of polypeptide sequence among family members, they are localized to different chromosomes.
RASMC HSPGs were analyzed further by immunoblotting with the monoclonal antibody 3G10 which specifically recognizes desaturated uronates on the heparan sulfate stubs that remain associated with core proteins after heparitinase digestion [ 37 ] . Complete digestion of RASMC lysates with heparitinase reveals major bands at 46 kDa and 70 kDa, indicating that these are the sizes of the major HSPG core proteins (not shown).
It is possible that heparin, heparan sulfate and dermatan sulfate inhibit III1-C mediated cell adhesion and ERK1/2 activation due to common chemical features.
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