Example sentences for: hepadnaviral

How can you use “hepadnaviral” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is the predicted phenotype for an RNAseH-deficient hepadnaviral P protein, and it indicates that the P protein has an RNAseH activity that acts on endogenously synthesized RNA:DNA heteroduplexes.

  • The hepadnaviral RNAseH activity has not yet been directly measured in viral core particles, however, its existence is inferred from four observations, (i) Sequence alignment of P with known RNAseH enzymes reveals conserved motifs in P [ 17, 18, 19, 20].

  • Understanding the mechanism of the template/substrate commitment of the hepadnaviral reverse transcriptase may need to wait until a three-dimensional structure of the polymerase bound to a nucleic acid primer-template is obtained.

  • The hepadnaviral DNA polymerase activity is strongly associated with the viral core structure and is normally unable to synthesize DNA from an exogenous template [ 16].

  • (ii) Mutation of the putative RNAseH active site residues in both Hepatitis B Virus (HBV) and duck hepatitis B virus (DHBV) P blocks synthesis of mature hepadnaviral DNA and results in the expected RNA:DNA heteroduplex [ 19, 21, 22, 23].


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