Words similar to heparin-binding
Example sentences for: heparin-binding
How can you use “heparin-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:
Fibronectin contains three types of homology sequences, I-III; type I sequences bind heparin, Staphylococcus aureus, fibrin, and cell surfaces, type II sequences bind collagen and gelatin, and type III sequences bind DNA, cell surfaces, heparin, and fibulin-1 [ 40 43 ] . Fibulin-1 interacts with fibronectin through a heparin-binding region in type III 13 repeat; the binding of fibulin-1 to this site is independent of the binding of heparin as addition of exogenous heparin does not inhibit fibulin-1 binding to fibronectin [ 40 ] . The fibronectin-binding site in fibulin-1 is located in EGF-like modules 5 and 6 [ 44 ] ; the binding of fibulin-1 to fibronectin is a heterotypic interaction in which an EGF-like module binds to a non EGF-like domain (the type III 13 fibronectin repeat) [ 40 ] .
The gene immediately centromeric to, and 12,840 bp from, SLC4A9 is HEGFL, which encodes a heparin-binding member of the EGF family.
the interaction of fibulin-1C with aggrecan and versican) between extracellular matrix proteins argues for the interaction of the EGF-modules containing within fibulin-1C and LTBP-3 with either the heparin-binding region or with the EGF-like domain of HB-EGF.
The interaction of fibulin-1C may map to the heparin-binding region of the extracellular domain of proHB-EGF or it may map to the EGF-like module of proHB-EGF or it may map to both of these regions within proHB-EGF.
The amino acid sequence of the heparin-binding region of HB-EGF ( 21KRKKKGKGLGKKRDPCLRKYK 41) [ 2 ] has been shown to have a strong affinity for heparin and may influence the interaction of this growth factor with cell-surface negatively charged heparan sulfate proteoglycans [ 22 ] . It remains to be seen whether specific/all of the EGF-like modules are required and whether calcium is needed for the interaction of HB-EGF with LTBP-3.
Loading...