Words similar to haplotypes
Example sentences for: haplotypes
How can you use “haplotypes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.
In our G3 RH map CES1 was located outside a subsequently refined Blau syndrome interval that excluded several cM centromeric to D16S408, thus confirming the lack of association between CES1 haplotypes and the disease phenotype.
The two most significant three-marker haplotypes identified in the moving-window analysis were D1S229-allele 7/D1S490-allele 7/D1S227-allele 5 and D1S2616-allele 6/D1S549-allele 12/D1S2641-allele 10.
A significantly increased absolute frequency of the haplotype A*03-B*35 has also been reported in hemochromatosis patients in Italy [ 29 ] . The present observations regarding this haplotype may be attributable to the large subgroup of persons of Italian and Sicilian descent in central Alabama [ 44 ] . A significantly increased frequency of the haplotype A*03-B*15 was observed in the present Alabama hemochromatosis probands, whereas a relative increase in this haplotype was detected in hemochromatosis cohorts in Brittany and Utah only after "correction" of the data for the preponderance of other haplotypes [ 2 20 ] . Similarly, a significantly increased frequency of the haplotype A*03-B*44 was observed in the present Alabama hemochromatosis probands, whereas a relative increase in this haplotype was detected in hemochromatosis cohorts in Sweden, Brittany, and Utah after "correction" of the data for the preponderance of other haplotypes [ 2 8 19 ] . The absolute frequency of the haplotype A*03-B*47 was increased in central Alabama hemochromatosis probands, whereas a "corrected" frequency of A*03-B*47 was increased in hemochromatosis patients from Denmark [ 8 ] . The other aforementioned haplotypes (except A*03-B*07 and A*03-B*14) have not been reported to occur with increased frequency in any hemochromatosis cohort from locations other than Alabama.
Relationships of HLA Phenotypes and Haplotypes to Immunoglobulin Phenotypes
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