Example sentences for: haplotypes

How can you use “haplotypes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Malawian sample included 21 different haplotypes, 13 of which were shared with the Gambian population (Table 2, Figure 2).

  • The 'star-shaped' genealogy of the Gambian TNF locus, dominated by one central haplotype with many derived haplotypes defined by single mutational events, produces negative disequilibria between most pairs of SNPs (the rare alleles are found in the repulsion phase).

  • Despite this common genetic background, phenotypic expression of sickle cell disease is widely variable, ranging from a mild, asymptomatic course with survival into the sixth or seventh decade to a very severe course with multi-organ damage and early mortality [ 1 ] . Some of the genetic factors contributing to this phenotypic diversity (particularly those linked to the globin genes, i.e. α-thalassemia and β-globin gene cluster haplotypes) have been well recognized [ 2 ] .

  • Frequencies of HLA-A and -B Haplotypes

  • More than two-thirds of the present 195 index patients who were evaluable for haplotyping inherited one or two of the significantly associated haplotypes A*01-B*08, A*02-B*44, A*03-B*07, A*03-B*14, A*31-B*40, and A*32-B*14.


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