Example sentences for: hap

How can you use “hap” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Dear Hap,

  • This alignment could be extended to the enzymatic core of three characteristic Mg 2+-dependent endonucleases: the bovine DNAseI [ 29 ] and two apurinic/apyrimidinic (AP) DNA-repair endonucleases, i.e. the E. coli Exonuclease III [ 30 ] and the human HAP1 protein [ 31 ] . These nucleases share the same catalytic residues and form a similar four-layered α/β-sandwich motif.

  • The transcription factors Ecm22p and Upc2p have been shown to induce the expression of ergosterol biosynthesis genes in response to low intracellular concentrations of ergosterol, whereas Hap1p is known to regulate the expression of these genes according to the availability of heme and oxygen, which are required for the pathway [ 43 44 ] .

  • Genes with a conserved half-site for the Hap1p transcription factor, as well as a conserved Ecm22p/Upc2p binding site in their TCRs, were significantly associated with induction in the presence of drugs that inhibited ergosterol biosynthesis (Figure 5b).

  • Some of the binding-site occurrences shown in Figure 6are likely to have occurred by chance (especially for sequences that are common in the genome, such as the Hap2/3/4p-, Mig1p-, and Msn2/Msn4p-binding sites).


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