Example sentences for: haplotype

How can you use “haplotype” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The increased frequency of haplotype 1 in the Gambian sample has a profound impact on the allelic associations between SNPs as evaluated by chi-square test or as defined by the pairwise association efficiency parameter.

  • In the Gambian sample, we observed 24 different haplotypes, and the distribution was dominated by one major haplotype (37.

  • Further, this implies that putative Ch6p alleles associated with CVID or IgGSD susceptibility occur on many HLA haplotypes that are common in Caucasians in central Alabama [ 10 ] and in Caucasians from a large national bone marrow donor program [ 14 ] . The present observations also confirm and extend the reports of association of HLA haplotype A*01-B*08 (or an extended haplotype containing A*01 and B*08) with heritable forms of immunoglobulin deficiency demonstrated in family-based analyses [ 3 6 19 20 21 22 ] . It is likely that a candidate gene(s) for CVID or IgGSD exists in the HLA class II region, [ 6 19 20 21 22 23 ] . Because the class II region is closer to the HLA-B locus than to the HLA-A locus, it is plausible that candidate gene(s) for CVID or IgGSD in the class II region are in greater linkage disequilibrium with HLA-B than HLA-A.

  • This integration of family- and population-based methods of haplotype reconstruction resulted in phase assignments of high certainty.

  • In Alabama subjects with hemochromatosis, the A*03-B*07 haplotype is not invariably associated with inheritance of C282Y.


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