Words similar to haplotype
Example sentences for: haplotype
How can you use “haplotype” in a sentence? Here are some example sentences to help you improve your vocabulary:
When the executive attention scores for subjects carrying the C1460T (T), LPR (3-repeat) haplotype were compared with executive attention scores for subjects carrying the C1460T (C), LPR (4-repeat) haplotype, modestly significant differences (P = 0.03) were observed.
Absolute or "uncorrected" values of A and B phenotype frequencies in index cases, A and B haplotype frequencies, and occurrence of two-haplotype combinations were calculated after enumeration of the raw data.
The eight remaining CFEOM pedigrees were too small to produce statistically significant lod scores; however, seven of the eight families displayed haplotype and
This disorder is typically associated with homozygosity for the C282Y mutation of the HFE gene (exon 2, nt 845 G→A) on Ch6p [ 1 ] . C282Y lies within an ancestral haplotype which includes the human leukocyte antigen (HLA) haplotype A*03-B*07 [ 2 3 4 5 ] . The ancestral haplotype is the predominant hemochromatosis-associated haplotype in many northwestern European countries, including Ireland [ 6 ] , Brittany [ 2 ] , Denmark [ 7 8 ] , Sweden [ 9 ] , and Germany [ 10 11 ] . This is attributed to the origin of the C282Y mutation on an A*03-B*07 haplotype in northwestern Europe and its early dissemination by Vikings [ 3 12 ] . Modification of the ancestral chromosome by recombination and admixture as a result of geographic migration explains the occurrence of chromosomes bearing C282Y in association with different HLA haplotypes [ 2 4 8 13 14 15 16 ] . Thus some non-ancestral haplotypes also occur with significantly increased frequencies in hemochromatosis patients in various countries in Europe and in descendants of Europeans [ 5 16 ] .
In spite of the significant differences in haplotype distributions between the two African populations, it appears that most of the haplotypes have evolved over a period of time during which there was gene flow between the two sampled populations.
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