Example sentences for: haplotype

How can you use “haplotype” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, 33 of 55 patients with the 229/490/227 haplotype (60%) also bore allele 6 of D1S2616, while 14 of 28 individuals with the 2616/549/2641 haplotype also bore allele 5 of D1S227.

  • In spite of the significant differences in haplotype distributions between the two African populations, it appears that most of the haplotypes have evolved over a period of time during which there was gene flow between the two sampled populations.

  • This is consistent with evidence for the occurrence on Ch6p of multiple distinct susceptibility genes for patterns of immunoglobulin deficiency, some recessive and others dominant [ 20 ] . For example, at least two putative alleles associated with heritable IgA deficiency occur on Ch6p, and each is associated with a different major histocompatibility (MHC) region haplotype [ 22 23 ] , whereas a putative susceptibility locus on chromosome 18 is not a major contributor to selective IgA deficiency [ 24 ] . Allele(s) on chromosomes other than Ch6p may also influence the phenotypic expression of CVID and IgGSD in adults.

  • DRB alleles associated with the DR4 haplotype, are intermediate between the two extremes.

  • Absolute or "uncorrected" values of A and B phenotype frequencies in index cases, A and B haplotype frequencies, and occurrence of two-haplotype combinations were calculated after enumeration of the raw data.


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