Words similar to haplotypic
Example sentences for: haplotypic
How can you use “haplotypic” in a sentence? Here are some example sentences to help you improve your vocabulary:
We developed an algorithim that chooses SNPs, first individually, then in multi-SNP haplotypes, that maximize entropy [ 35 ] . Thus we can define a subset of SNPs that represent the greatest proportion of the full 12-SNP haplotypic diversity.
The second technique, entropy maximization method (EMM), selects those SNPs that most effectively dissect the underlying haplotypic structure of a locus.
Entropy ( E ), a measure of haplotypic diversity, was calculated for the full 12-SNP haplotypes in each population (Equation (4) in Materials and methods).
Depending on the haplotypic structure of a gene region, one may be able to choose a small subset of SNPs that capture most of the haplotypic diversity, thus reducing the cost of genotyping significantly with only modest reductions in information [ 20 21 22 ] . Two methods have been reported that select the best subset of SNPs [ 20 23 ] . In this paper we introduce a third, the entropy maximization method (EMM), which chooses the subset of SNPs that explains the largest proportion of the underlying haplotypic diversity as measured by entropy.
This method provides for the selection of optimal haplotype-tagging SNPs even in the absence of a clear haplotypic block structure.