Example sentences for: haplotypic

How can you use “haplotypic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We developed an algorithim that chooses SNPs, first individually, then in multi-SNP haplotypes, that maximize entropy [ 35 ] . Thus we can define a subset of SNPs that represent the greatest proportion of the full 12-SNP haplotypic diversity.

  • The second technique, entropy maximization method (EMM), selects those SNPs that most effectively dissect the underlying haplotypic structure of a locus.

  • Entropy ( E ), a measure of haplotypic diversity, was calculated for the full 12-SNP haplotypes in each population (Equation (4) in Materials and methods).

  • Depending on the haplotypic structure of a gene region, one may be able to choose a small subset of SNPs that capture most of the haplotypic diversity, thus reducing the cost of genotyping significantly with only modest reductions in information [ 20 21 22 ] . Two methods have been reported that select the best subset of SNPs [ 20 23 ] . In this paper we introduce a third, the entropy maximization method (EMM), which chooses the subset of SNPs that explains the largest proportion of the underlying haplotypic diversity as measured by entropy.

  • This method provides for the selection of optimal haplotype-tagging SNPs even in the absence of a clear haplotypic block structure.


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