Words similar to down-regulated

Example sentences for: down-regulated

How can you use “down-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

Since a number of gene promoters were hypermethylated and showed down-regulated mRNA in GCT, we wanted to test whether hypomethylation reactivates the gene expression in these tumors.
Also, numerous mitochondrial DNA template clones were down-regulated during this transition.
During the spherical to tubular transitions several genes were indicated using SSH to be down-regulated, such as thymosin-beta 4, mitochondrial cytochrome B, and F1Fo-ATP synthase complex mRNA.
Stimulation of RAR α and γ mRNA in LNCaP cells by T differed from that in normal rat prostate and non-tumorigenic rat prostate epithelial cells (NRP-152), but was comparable to that in tumorigenic rat prostate epithelial cells (NRP-154) [ 13 14 ] . In cervical carcinoma cells, the RAR β gene was abnormally down-regulated by RA [ 36 ] . In ER positive human breast cancer cells, RAR α mRNA was also up-regulated by estrogen [ 16 ] . Thus, T stimulation of RAR mRNAs in LNCaP cells could be related to the pathologic state of the cells.
II 135 and TBP components of the basal transcription machinery are down-regulated through proteolytic degradation.