Example sentences for: down-regulated

How can you use “down-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Another example of co-receptors with multiple functions is the leukotriene family member B4, which was down-regulated in Tat expressing cells (Acc# D89078, Table 1).

  • In prostate cells, however, SKP2 seems to be a major determinant of p27 degradation, as it is down-regulated by androgen and its overexpression is sufficient to mediate p27 ubiquitylation and degradation.

  • To our surprise, none of the three down-regulated genes studied exhibited differential expression in Northern blots when the cDNA fragments of these genes were used as probes.

  • Genes were chosen for further study by being up- or down-regulated by at least 2.5-fold compared to controls in at least one of the four probe pairs.

  • Consistent with an earlier report [16], rosiglitazone down-regulated resistin gene expression (Figure 4A) in LPS-stimulated human macrophages.


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