Words similar to down-regulated

Example sentences for: down-regulated

How can you use “down-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

II 135 and TBP components of the basal transcription machinery are down-regulated through proteolytic degradation.
Consequently, if differential expression is defined as greater than 2 SD from the mean, genes with fold changes greater than 1.5 can be classified as up- or down-regulated at approximately 95% confidence level.
A total of 69 and 43 templates were confirmed up and down-regulated, respectively, during the tubular to filamentous transition.
Levels of expression of each gene were assessed by comparing with the respective control values, obtained from the averages calculated from 2 to 4 normal testes, after normalization against ACTB . All tumors with promoter hypermethylation of the MGMT and MLH1 genes exhibited an absence or down-regulated expression of the respective gene, while 8 of 10 cases with RASSF1A methylation and 3 of 5 tumors with RARB methylation showed down-regulated expression (Table 1).
In the absence of SPARC, expression of transforming growth factor-β1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] . The expression of cell surface receptor for insulin-like growth factor I in SPARC-null embryonic fibroblasts is also diminished [ 16 ] . Studies with SPARC-null cells have confirmed that SPARC functions in cell proliferation.