Example sentences for: down-modulation

How can you use “down-modulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has long been known that infection by HIV-1 commonly leads to the down-regulation and the disappearance of CD4 receptors from the plasma membrane, a phenomenon referred to as receptor down-modulation.

  • Furthermore, it may be possible that low-RE TAA-specific T cells may interfere with elicitation of high-RE T cells, either by direct competition for antigen on APC surface [33,34] or down-modulation of peptide–MHC complexes.


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