Words similar to down-regulate

Example sentences for: down-regulate

How can you use “down-regulate” in a sentence? Here are some example sentences to help you improve your vocabulary:

Indeed, the use of a constitutively active mutant of PP1 has already been shown to result in pRB-dependent G1 arrest in human cancer cells [ 22 ] . Placing this mutant into the inducible expression system described here has the potential to down-regulate expression of wild-type endogenous PP1.
Consistent with this prediction, treatment with 0.3 μM norepinephrine for 24 h failed to down-regulate the receptor containing the motif mutated to EESSVAE, although the wild-type receptor with the EESSTSE motif was down-regulated by 35%.
It was reported that PPAR activation could down-regulate the activity of AP-1 by interfering with the functions of c-jun [ 36 37 ] . Therefore, the following set of experiments was designed to test if PPAR activation could reduce c-jun activation in 25-OH-cholesterol treated microglia.
Arrestins bind phosphorylated receptors and further down-regulate receptor activity by inhibiting G protein interaction.
10) have various expression levels of doubly spliced viral mRNAs, including Tat, Rev, Nef, Vpr, and other accessory proteins, we decided to perform the microarray in a system where Tat was constitutively expressed; asking whether Tat by itself, or in the absence of other accessory proteins, could still down-regulate host cellular genes.