Words similar to down-regulation

Example sentences for: down-regulation

How can you use “down-regulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

This result suggests that the proliferative effect of M6P/IGF2R down-regulation is likely the result of unchecked IGF-II stimulation.
Recent evidence suggests that lysosomal enzymes, such as cathepsins B and D contribute to TNF-induced apoptosis in vitro [ 35 36 37 38 ] and in vivo [ 39 ] . The M6P/IGF2 receptor has been shown to be involved in binding, transport and activation of lysosomal enzymes, including cathepsins [ 12 13 ] . Therefore, it is possible that down-regulation of the M6P/IGF2R results in improper trafficking and activation of cathepsins.
Current models propose that hormone binding inactivates the receptors, thus resulting in down-regulation of CTR1 activity.
Therefore, we wished to determine what effects the down-regulation of the EGFR would have on ERK signalling via the δ-OR.
In addition, downregulation of RB1 and accumulation in the underphosphorylated form paralleled SKP2 down-regulation (Fig.