Words similar to dn

Example sentences for: dn

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Interestingly, whereas a high percentage of the DN thymocytes expressed GFP after transduction (75%), the DP fraction was relatively refractory to transduction even though all of the DP cells expressed hCARΔcyt; less than 10% of the transduced DP cells were GFP-positive irrespective of the MOI tested (Fig.
Given the internally consistent actions of DN ROCK1 and CA ROCK1, as well as the results employing either FTI-1 or arachidonate, we concluded that the Y-27632 result might be due to inhibition by Y-27632 of protein kinases other than ROCK1 [23].
The possibility was also considered that cytotoxicity of Y-27632 for the central vacuolar pathway might explain the disparity between the effects of DN ROCK1 and those of Y-27632, but neither impairment of intracellular APP maturation nor increased apoptosis as measured by LIVE/DEAD assay were apparent following Y-27632 treatment (data not shown).
Cultures from control genotypes (wild type, Pax1 +/-, Hoxa3 +/-, Pax1 -/-) behaved as expected [ 41 42 43 44 45 46 ] , with addition of IL-7 causing an increase in the percentage of DN cells and a corresponding decrease in DP cells, while adding SCF had no significant effect on thymocyte development (data not shown).
This result was unexpected in light of the effects of DN ROCK1.