Example sentences for: dn

How can you use “dn” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, 140 clones in the PF00001 family had been hybridized with the probe pair of " PBMC Cells, Untx, 24 hr, Dn4625 vs t/2 4 hr ", of which 28 clones (20%) showed greater than two fold difference in the pair-wise comparison.

  • Conversely, DN ROCK1 alone activated shedding of sAPP α . Cellular levels of holoAPP were not affected by transfection (Figure 5; p < 0.05 versus GFP control).

  • This result was unexpected in light of the effects of DN ROCK1.

  • CA and DN Myc-tagged ROCK1 vectors were generated as previously described [30,31] and were generous gifts from Liqun Luo (Stanford University).

  • Mutations in TMC1 are responsible for the autosomal dominant human hearing disorder DFNA36 and for the recessive deafness DFNB7/11 [ 5 ] ; the corresponding murine gene Tmc1 also causes deafness in the mutant mouse strains Beethoven ( Bth ) and deafness ( dn ) [ 6 ] . Bth / Bth mice display altered potassium currents in early postnatal cochlear hair cells, in particular Ik,n and Ik,f currents appear to be depressed [ 10 ] . This observation led to the hypothesis that Tmc1 may participate directly or indirectly in regulating the permeability of potassium channels [ 10 ] . Because of the high level of conservation of the amino acid sequences among the eight mammalian TMC proteins (Figure 1, Additional file 1), we speculate that other TMC proteins may as well be modifiers of ion channels or transporters.


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