Words similar to dnaa
Example sentences for: dnaa
How can you use “dnaa” in a sentence? Here are some example sentences to help you improve your vocabulary:
unknown, but it may have a role in cell division [ 11 ] . RNase P, which consists of the protein subunit RnpA and a catalytic RNA subunit, is essential for generating mature tRNAs by cleaving the 5'-terminal leader sequences of precursor tRNAs [ 16 ] . rpmH encodes ribosomal protein L34, and DnaA is the initiator protein for chromosome replication.
The dnaA gene itself is divided into four domains that differ in the extent of sequence homology [ 34 ] . Domain IV is responsible for DnaA box recognition and domain III is a highly conserved region containing the ATP-binding site [ 13 35 ] . Domain I participates in cooperative DnaA protein-DNA interactions [ 36 ] .
The relative gene order in this region is also highly conserved in many bacteria, especially the Gram-positives [ 11 ] . Although intergenic sequences in this region are conserved only among closely related organisms, the DnaA box is found in the non-coding regions flanking dnaA in most bacteria studied [ 12 ] . DnaA boxes are conserved nucleotide sequences (TTGTCCACA) where the DnaA protein binds to DNA, triggering events that ultimately lead to replication initiation and DNA synthesis [ 9 ] .
The significance of additional dnaA boxes in M. paratuberculosis is likely necessary to open the DNA helix of this GC rich organism (69% GC content).
The oriC of Gram-positive bacteria typically contains 10 - 30 of these DnaA boxes, often found in non-coding regions flanking the dnaA gene.