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Example sentences for: dnaa
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The relative gene order in this region is also highly conserved in many bacteria, especially the Gram-positives [ 11 ] . Although intergenic sequences in this region are conserved only among closely related organisms, the DnaA box is found in the non-coding regions flanking dnaA in most bacteria studied [ 12 ] . DnaA boxes are conserved nucleotide sequences (TTGTCCACA) where the DnaA protein binds to DNA, triggering events that ultimately lead to replication initiation and DNA synthesis [ 9 ] .
[ 8] on the basis of the position of the only DnaA box present on the chromosome and on a shift in the GC-skew value at third codon positions around that region).
The M. smegmatis coding sequence, gnd , has similarity to the 6-phophogluconate dehydrogenase genes in E. coli , but the mycobacterial protein is predicted to be about 200 amino acids shorter than the E. coli homolog . The length of non-coding intergenic regions between rpmH - dnaA and dnaA - dnaN is well conserved among the bacteria shown in figure 2. In many bacteria where a functional oriC has been identified, this gene order is conserved and oriC is adjacent to the dnaA gene [ 9 10 19 ] .
In addition, a hexameric sequence thought to be recognized by ATP-DnaA (AGATCT) was found in the 3' non-coding sequence adjacent to dnaA (Fig.
Beginning with nucleotide number 1 in the dnaA coding region of each genome, a comparison of 2 million bases of M. paratuberculosis with 2 million bases from M. avium by Pustell DNA matrix analysis [ 25 ] , indicates that genomic similarity continues outside the surrounding oriC region (Fig.
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