Words similar to dnaa
Example sentences for: dnaa
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The Gram-positive organisms in this study harbor 10 - 30 DnaA boxes (with 1 - 3 mismatches from the consensus sequence TTGTCCACA) flanking the dnaA sequence [ 8 20 21 22 23 ] and 35 were found surrounding the M. paratuberculosis dnaA gene (Fig.
The dnaA gene itself is divided into four domains that differ in the extent of sequence homology [ 34 ] . Domain IV is responsible for DnaA box recognition and domain III is a highly conserved region containing the ATP-binding site [ 13 35 ] . Domain I participates in cooperative DnaA protein-DNA interactions [ 36 ] .
In addition, a hexameric sequence thought to be recognized by ATP-DnaA (AGATCT) was found in the 3' non-coding sequence adjacent to dnaA (Fig.
The significance of additional dnaA boxes in M. paratuberculosis is likely necessary to open the DNA helix of this GC rich organism (69% GC content).
Beginning with nucleotide number 1 in the dnaA coding region of each genome, a comparison of 2 million bases of M. paratuberculosis with 2 million bases from M. avium by Pustell DNA matrix analysis [ 25 ] , indicates that genomic similarity continues outside the surrounding oriC region (Fig.