Example sentences for: dnaa

How can you use “dnaa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The dnaA gene is divided into four functional domains based on analysis of several dnaA mutants [ 24 ] . These domains consist of (1) an area near the N-terminus thought be involved in ability of the DnaA protein to aggregate, (2) ATP binding, (3) a domain that maps to a region near the C-terminus and is involved in DNA binding, (4) and a final domain of unknown function, but may bind DnaB.

  • For instance, DnaA monomers bind to specific, non-palindromic 9-nucleotide sequences called DnaA boxes, and this interaction is thought to initiate replication.

  • The Gram-positive organisms in this study harbor 10 - 30 DnaA boxes (with 1 - 3 mismatches from the consensus sequence TTGTCCACA) flanking the dnaA sequence [ 8 20 21 22 23 ] and 35 were found surrounding the M. paratuberculosis dnaA gene (Fig.

  • An AT-rich stretch of 19 nucleotides (74% A+T), which in other bacteria serves as the site of local unwinding of DNA after DnaA-DNA interaction, was located in non-coding sequence adjacent to dnaA (Fig.

  • The relative gene order in this region is also highly conserved in many bacteria, especially the Gram-positives [ 11 ] . Although intergenic sequences in this region are conserved only among closely related organisms, the DnaA box is found in the non-coding regions flanking dnaA in most bacteria studied [ 12 ] . DnaA boxes are conserved nucleotide sequences (TTGTCCACA) where the DnaA protein binds to DNA, triggering events that ultimately lead to replication initiation and DNA synthesis [ 9 ] .


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