Example sentences for: cgmp

How can you use “cgmp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The activated response was measured in the same oocyte at 3-5 minutes after addition of 4 mM sodium nitroprusside (SNP), which elevates endogenous cGMP levels.

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.

  • Finally, we found that the increases in ser 16-HSP20 phosphorylation were not explained by increases in [cAMP] or [cGMP] at the end of heat treatment (Fig.

  • And 3) Are increases in [cAMP] or [cGMP] responsible for the heat-induced increases in ser 16-HSP20 phosphorylation?

  • 1 has specific binding sites to 17β-estradiol on the cell surface, and estradiol exposure increases the cellular pH, cAMP, cGMP and intracellular calcium [ 29].


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