Words similar to cgrp

Example sentences for: cgrp

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This putative association is strengthened by finding for the first time that targeting of RIα requires the AKAP binding surface [ 17 ] . Yotiao is another AKAP enriched at the NMJ, but appears to bind only RII [ 30 ] . PKA phosphorylates the nAChR when stimulated at the synapse by the neuropeptide CGRP and by adenosine from muscle responding to acetylcholine [reviewed by [ 31 ] ]. This phosphorylation may regulate the degradation of the nAChR [ 32 ] . Consistent with the action at the presynapse, it was shown that PKA facilitation of acetylcholine release is dependent on nerve endplate calcium concentration [ 33 ] . Based on our observation of colocalization with synaptophysin at presynaptic vesicles, RIα may be the isotype that influences this release of neurotransmitter.
Consistent with the important role of the dorsal horn of the spinal cord in pain transmission and modulation, neurochemical studies have implicated an enriched expression of neurotransmitters, neuropeptides, ion channels, and receptors in these neurons, including substance P, enkephalin, CGRP, somatostatin, and GABA.