Words similar to cgh
Example sentences for: cgh
How can you use “cgh” in a sentence? Here are some example sentences to help you improve your vocabulary:
Examples of some of the uses and technologies supported include: one- and two-color spotted arrays (cDNAs, PCR products, or oligonucleotides) on glass or nylon, in situ synthesized oligonucleotides (Affymetrix/photolithography, ink-jet), RNA abundance (gene expression, polysome profiling), and DNA abundance (array-CGH, chromatin immunoprecipitation, genotyping).
In this study, we apply CGMA analysis to a large hepatocellular carcinoma microarray dataset to demonstrate its validity as an alternative to CGH and to identify candidate genes in regions of frequent cytogenetic change.
Comparative genomic hybridization (CGH), originally described by Kallionemi in 1992, is an ideal screening measure, allowing the simultaneous detection of gains, losses and amplifications in genetic information in an individual tumor [ 9 ] . In addition, several authors have used the total number of chromosomal abnormalities as an assessment of genomic instability [ 10 ] . In this study, CGH analysis showed the presence of significant overlap in genomic instability and in the individual chromosomal abnormalities based on the degree of tobacco/alcohol exposure in HNSCC, with the exception of gains/amplifications at 3q and 1p.
Two landmark CGH analyses identified 12 different regions of frequent imbalance.
Through the examination of hepatitis B virus (HBV) - and hepatitis C virus (HCV)-induced tumors, two landmark CGH studies have suggested that a subset of cytogenetic changes frequently occurs in HCC [ 11, 12].
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