Example sentences for: cgma

How can you use “cgma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether gene-expression data could be used to identify cytogenetic changes accurately, we applied CGMA to a microarray dataset of HCC tumors and compared the CGMA predictions to existing CGH data.

  • In contrast, tumor nodules from patient HK64 have very similar gene-expression profiles and very similar cytogenetic profiles as predicted by CGMA, suggesting that these tumors have common origins and these nodules have not diverged significantly from the original lineage.

  • The set of genes that are consistently misregulated in regions of frequent cytogenetic change as predicted by CGMA are shown in Table 2. Platelet-derived growth factor receptor alpha is consistently downregulated in a region of frequent cytogenetic loss and this suggests that loss of a member of this receptor gene family is important in HCC progression.

  • CGMA also detected three regions that have not been implicated by these CGH studies.

  • CGMA predicts chromosomal amplifications and deletions by organizing gene-expression data by genomic mapping location and scanning for regions that contain a statistically significant number of gene-expression values that change in the same relative direction.


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