Words similar to cdkn
Example sentences for: cdkn
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Another group of genes encoding three enzymes (PLK (Polo-like kinase), CDKN3 (cyclin-dependent kinase inhibitor 3/p27-Kip1), CDC25A (cell division cycle 25A)) and a transcription factor (E2F1, E2F transcription factor 1) involved in the control of the cell cycle were grouped (Figure 7g).
These two elements control, respectively, the allele-specific expression of the H19/Igf2/Ins2 gene cluster, and the second gene cluster containing Kcnq1, the antisense transcript Kcnq1ot1, p57 Kip 2/ Cdkn1c, Slc22a1l, Ipl/Tssc3 and possibly additional genes [ 1 2 ] . There is good evidence assigning one border of the overall imprinted region to the DNA immediately downstream of H19 [ 3 ] . However, the other border, which must lie upstream of Ipl is less well-defined [ 4 ] . Here we show evidence for weak imprinting of a gene, Tnfrh1 , which is located upstream of
The promoters of CDKN2A , MGMT , BRCA1 , TP73 , TIMP3 , GSTP1 , and MLH1 genes were rarely (<10% cases) methylated.
Other genes, FHIT (11%), APC (11%), CDKN2A (8.
The primers used for amplification of methylated and unmethylated promoters of genes RARB , TIMP3 , CDKN2A , p14 ARF , MGMT , DAPK , CDH1 , GSTP1 , APC promoter 1A, RB1 , MLH1 , TP73 , BRCA1 , FHIT , and HIC1 have been described previously http://pathology2.jhu.edu/pancreas/prim0425.htm#MSP; [ 32 47 48 49 ] . Methylated (MF and MR) and unmethylated (UF and UR) primers for RASSF1A promoter were designed according to Herman et al [ 46 ] and as described earlier [ 50 ] . PCR products were run on 2% agarose gels and visualized after ethidium bromide staining.
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