Words similar to cdkn

Example sentences for: cdkn

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These two elements control, respectively, the allele-specific expression of the H19/Igf2/Ins2 gene cluster, and the second gene cluster containing Kcnq1, the antisense transcript Kcnq1ot1, p57 Kip 2/ Cdkn1c, Slc22a1l, Ipl/Tssc3 and possibly additional genes [ 1 2 ] . There is good evidence assigning one border of the overall imprinted region to the DNA immediately downstream of H19 [ 3 ] . However, the other border, which must lie upstream of Ipl is less well-defined [ 4 ] . Here we show evidence for weak imprinting of a gene, Tnfrh1 , which is located upstream of
Other genes, FHIT (11%), APC (11%), CDKN2A (8.
The primers used for methylated and unmethylated-specific PCR for genes RARB , TIMP3 , CDKN2A , p14 ARF , MGMT , DAPK , CDH1 , GSTP1 , APC promoter 1A, RB1 , MLH1 , TP73 , BRCA1 , FHIT , and HIC1 have been described previously http://pathology2.jhu.edu/pancreas/prim0425.htm#MSP; [ 34 35 36 37 ] . For additional genes, we designed the following gene-specific primers for methylated (MF and MR) and unmethylated (UF and UR) sequences according to Herman et al [ 33 ] :
Contrary to the previous reports, we found a low frequency of p16/CDKN2A gene promoter methylation [ 12 13 28 29 ] . The reason for these differences is currently unclear.
1%; RASSF1A , 10%; APC , 10%; CDKN2A , 8.9%; MGMT , 6.7%; BRCA1 , 5.6%; TP73 , 2.2%; TIMP3 , 1.1%; GSTP1 , 1.1%; and MLH1 , 1.1% (Table 1).