Words similar to cdk-
Example sentences for: cdk-
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As most of the cells in the larval fat body, salivary gland and midgut are polyploid (reviewed in [ 40]), the array hybridizations are in good agreement with the known function of Cdk-1 .
Mutations in Cdk-1 drive cells that would normally remain diploid into endoreplication [ 39].
The expression profile of the cyclin-dependent kinase 1 ( Cdk-1/cdc2 ), is also noteworthy.
It associates specifically with unduplicated centrosomes, and its phosphorylation by CDK-2/cyclin E, the trigger for centrosome duplication, is required for duplication to occur [ 17 ] . The nucleophosmin gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase in cases of this disease with (2;5)(p23;q35) translocations [ 18 ] . The nucleophosmin portion contributes to transformation by providing a dimerization domain, which allows activation of the fused kinase and signal transduction [ 19 ] .
We found Cdk-1 (CG5363) to be repressed in larval tissues when compared to imaginal discs (Figure 9).