Words similar to cdh
Example sentences for: cdh
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Such differences in the two major histologies have also been reported previously for DAPK , HIC1 , and APC genes [ 13 ] . However, we found CDH1 promoter methylation restricted to SCC in the present study, while Dong et al found methylation in both histological types [ 13 ] . This difference may be due to small number of AC patients we studied.
To examine the biological role of promoter methylation in CC, we assessed the levels of mRNA by semi-quantitative RT-PCR in eight cell lines and compared with the respective control values obtained from the averages calculated from 2 normal cervix after normalization against ACTB . This analysis was performed on 7 genes ( CDH1 , DAPK , RARB , HIC1 , MGMT , RASSF1A , and MLH1 ) that exhibited methylation in one or more cell lines and primary tumors (Fig.
6%; APC , 9.8%; RARB , 7.6%; CDH1 , 7.6%; FHIT , 6.5%, MLH1 , 4.3%; TIMP3 , 3.3%; GSTP1 , 1.1%; and NME2 , 1.1% (Fig.
The CDH1 , DAPK , RARB , and HIC1 gene promoters were frequently methylated.
4%) have also reported a similar overall high frequency of promoter methylation [ 12 13 ] . We identified promoter methylation in >25% cases in CDH1 , DAPK , and RARB genes, while it was less frequent (10-25% cases) in HIC1 , FHIT , RASSF1A , and APC genes in CC patients.
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