Example sentences for: cdh

How can you use “cdh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The CDH gene exhibited a complete absence of expression in one cell line (SW756) that showed promoter hypermethylation and two other cell lines (C-33A and SiHa) without evidence of methylation (Fig.

  • 7%) showed absent or reduced expression suggesting that CDH1 inactivation is a later event in CC development.

  • Of these, 15 genes ( MGMT , RASSF1A , APC , RARB , CDH1 , MLH1 , TIMP3 , GSTP1 , DAPK , CDKN2A , p14 ARF , BRCA1 , FHIT , TP73 , and HIC1 ) had previously been shown to be commonly methylated in various solid tumor types [ 4 ] . Six additional genes ( RB1 , NME1 , NME2 , BTG1 , NEDD1 , and APAF1 ) were studied because of their possible involvement in genetic alterations in GCT as indicated by LOH studies [ 8 9 10 ] . The RB1 gene at 13q14.

  • Cdc14 subsequently dephosphorylates (and thereby activates) proteins involved in Sic1 expression (Swi5) and C1b degradation (Hct1/Cdh1) [ 19 41 50 ] , thereby eliminating mitotic Cdk activity and promoting exit from mitosis.

  • In S. cerevisiae, a key event accompanying exit from mitosis is the inactivation of Clb/Cdc28 protein kinase achieved through degradation of Clb and accumulation of the Clb/Cdc28 inhibitor Sic1 (reviewed in [ 1 ] ). Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase and its substrate specific activator Hct1/Cdh1 are required for degradation of Clb2, the major mitotic cyclin in the budding yeast (reviewed in [ 2 ] ). Whereas hct1Δ and sic1Δ cells appear relatively normal,


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast