Words similar to amplifications

Example sentences for: amplifications

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We have previously shown that subsets of resistant tumors exhibit TP53 gene mutations and chromosomal amplifications [ 6 ] . However, the role of MGMT in GCT sensitivity or resistance to chemotherapy is not known.
The point mutation and deletion mutation were constructed by a method involving oligonucleotides synthesized to contain a mutation in combination with wild-type oligonucleotides in PCR amplifications of fragments of the cDNA.
PCR amplifications of cDNA inserts were carried out at annealing temperatures of 50°C (614 and 606 libraries) or 60°C (707 library) in a 25 μl volume in a GeneAmp PCR system 9700 (Applied Biosystems, Foster City, CA) thermocycler for 35 cycles with a 2 min extension time.
The sense primer sequences are as follows: BTBD1: U1 (395-482aa) 5'-GACCCCGGGGAATGATACCGGCTTTAGTTGTGA-3', U2 (342-482aa) 5'-GACCCCGGGCTGGGGTTACAGTGGGACGAGT-3', U3 (213-482aa) 5'-GACCCCGGGAAGTGCAGAAGGGTTTACT-3', U4 (303-482aa) 5'-GACCCCGGGAAACCTCTTTCTTCATTTTACTGT-3', The same antisense primer was used for all amplifications: 5'-CGGAATTCTTTGTGGCCATTTATGTTTTTGAC-3'.
Of the 963 original amplifications (carried out by RGI), 45 (4.