Example sentences for: agonist

How can you use “agonist” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phosphorylation of cPLA 2 on Ser 505has been hypothesized to play a role in Ca 2+-mediated translocation since Ser 505phosphorylation is required for cPLA 2 -mediated AA release in response to low-dose, but not high-dose, ionophore [ 22 ] . Translocation of cPLA 2 S505A in CHO cells has been reported in response to ionophore stimulation [ 25 ] , but the effect of Ser 505phosphorylation on the kinetics of translocation, targeting, and in response to a physiological agonist was not investigated.

  • At 200 nM of agonist 1 , RAR-β was 50% active, RAR-γ 25% and RAR-α 5% active.

  • The dorsal spinal cord marker Pax7 is normally repressed by low concentrations of Hh [ 22 ] . Pax7 expression was extinguished by 1-10 nM agonist (Figure 2b,c,d,e,f).

  • These results demonstrate that the binding of the agonist to Smo is reversible and that equilibrium binding will require binding reaction times of approximately 50 hours (five times the t½ of dissociation).

  • Considering our experimental conditions, particularly using a single in vivo injection, the dermenkephalin seemed the most suitable agonist ligand to specifically stimulate the δ-opioid receptor and provoke a possible internalization of the receptor due to its affinity as well as to its strong resistance to degradation.


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