Example sentences for: agonist

How can you use “agonist” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After 15 minutes of incubation, the agonist was added and the cells were incubated with both ligands for an additional 10 minutes.

  • [ 3H]PGE 2 binding was partially displaced by the EP 2/3/4 agonist misoprostol and was not displaced by the EP 1/3 agonist sulprostone (Fig.

  • To control for this observation, we added an unlabeled, inactive Hh agonist to the binding assay at 2 μM (a 1000-fold molar excess).

  • A recent study examined effects of PPARα-specific induction in murine livers using cDNA microarrays [ 30 ] . Despite the different strain of mice examined (C57BL/6J) and the different genomic technology utilized for the examination of differentially expressed genes (cDNA microarrays), several genes were found differentially regulated in both experiments, indicating that the PPAR agonist and LC-PUFA affect gene expression through similar pathways.

  • Down-regulation occurs after prolonged agonist treatment (hours to days), resulting in a loss of receptor binding sites [ 2 3 4 ] . The processes involved in homologous desensitization have been extensively investigated for the beta-2 adrenergic receptor, which is the prototypical G protein-coupled receptor.


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