Example sentences for: agonist

How can you use “agonist” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The authors suggest that morphine has low intrinsic activity at μ-opioid receptor compared for instance to the lower affinity μ agonist [D-Ala 2,N-MePhe 4,Gly 5-ol]enkephaline (DAMGO) which is able to trigger an internalization process.

  • Recently, Sixma and colleagues have determined the first high-resolution structure of a soluble acetylcholine binding protein (AChBP), extracted from snail neurons, and homologous to the ligand binding domain of nAChR [ 6 ] . Based on this high-resolution crystal structure, we have built an atomic model of the agonist binding site of nAChR, and docked acetylcholine and nicotine to different receptor isotypes.

  • Combining LG1069 with the inverse agonist androstanol resulted in a partial block in its inhibitory effect and an intermediate level of activity.

  • Finally, with increasing concentrations of Hh protein and the agonist there is a clear dose-dependent increase of HA-Smo levels (Figure 5d).

  • Similar results were seen at higher doses of agonist (up to 2 μM) and in several independent lines (data not shown).

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