Words similar to agonist

Example sentences for: agonist

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Phosphorylation of cPLA 2 on Ser 505has been hypothesized to play a role in Ca 2+-mediated translocation since Ser 505phosphorylation is required for cPLA 2 -mediated AA release in response to low-dose, but not high-dose, ionophore [ 22 ] . Translocation of cPLA 2 S505A in CHO cells has been reported in response to ionophore stimulation [ 25 ] , but the effect of Ser 505phosphorylation on the kinetics of translocation, targeting, and in response to a physiological agonist was not investigated.
At 200 nM of agonist 1 , RAR-β was 50% active, RAR-γ 25% and RAR-α 5% active.
The dorsal spinal cord marker Pax7 is normally repressed by low concentrations of Hh [ 22 ] . Pax7 expression was extinguished by 1-10 nM agonist (Figure 2b,c,d,e,f).
These results demonstrate that the binding of the agonist to Smo is reversible and that equilibrium binding will require binding reaction times of approximately 50 hours (five times the t½ of dissociation).
Considering our experimental conditions, particularly using a single in vivo injection, the dermenkephalin seemed the most suitable agonist ligand to specifically stimulate the δ-opioid receptor and provoke a possible internalization of the receptor due to its affinity as well as to its strong resistance to degradation.