Words similar to agonism
Example sentences for: agonism
How can you use “agonism” in a sentence? Here are some example sentences to help you improve your vocabulary:
All other ligands studied showed agonism at μ opioid receptor with varying maximal effects or efficacies ranging from 29% - 71% (Table 1).
For example some investigators have suggested that opioid ligands with agonism at μ opioid receptors and antagonism at δ opioid receptors are potentially useful analgesics [ 5 6 7 ] . In cases where the medicinal effect of a drug is mediated through the same opioid receptor type that also elicits the side effects, the use of drugs with mixed activity could be most beneficial [ 7 ] . In such a case, interaction with one receptor could reverse the unwanted side effects associated with activation of the other receptor.
(3) These in vitro data can be utilized to define the physiochemical features of the ligands defining agonism and antagonism at δ opioid receptors, leading to design and discovery of novel opioid analgesics.
Clinically, xorphanol is a well tolerated, orally active analgesic that provides effective pain relief but shows low physical dependence liability [ 29 30 ] . It is possible that the low physical dependence liability of this drug is due to its partial agonism at μ opioid receptors.
Agonism
Loading...