Words similar to agonistic

Example sentences for: agonistic

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This ligand had been described as a mixed agonist-antagonist opioid ligand [ 30 31 ] with agonistic activity at κ opioid receptors [ 32 ] . Overall very little work has been done on xorphanol and little is known about it except that it is an orally active analgesic with limited physical dependence liability [ 30 ] . Thus the present report describing its activity at δ opioid receptors provides useful data on this ligand.
Compounds with very little in vitro agonistic activity (<20% inhibition of cAMP production) for which the dose response curves could not be fitted, were tested for antagonism.
To determine whether costimulation through human CD81 affected these early activation events, peripheral blood cells from normal CMV seropositive donors were incubated for 6 h with a superantigen, SEB, or the viral antigen, CMV, in the presence or absence of an agonistic anti-CD81 mAb, 5A6.
Still, other reports, have suggested that opioid ligands with agonistic effect at μ opioid receptors and antagonistic effect at δ opioid receptors are potentially useful analgesics [ 3 17 18 ] . These latter results advocate that the key to designing opioid ligands with optimal analgesia and minimal side effects may be in the design of ligands that act on more than one receptor type, but activate each receptor differently.
Agonistic activity of opioid ligands was assessed by measuring the inhibitory effect of the ligands on forskolin-stimulated cAMP accumulation.