Example sentences for: agonist-bound

How can you use “agonist-bound” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is consistent with the notion that corepressors restrict the activity of agonist-bound ERβ-LBD.

  • Since ERβ bound N-CoR and SMRT in the presence of estrogens, we investigated the possible involvement of corepressors in the actions of agonist-bound ERβ in vivo . To perform this experiment, we examined the effect of the HDAC inhibitor trichostatin A (TSA) on ERβ activity in transiently transfected HeLa cells.

  • By contrast, a peptide corresponding to GRIP1 NR box 2 did compete for this interaction [ 40 41 ] . This finding suggests that agonist-bound ERβ does not recognize ID motifs, and that ERβ interactions with N-CoR more closely resemble those with GRIP1.

  • [ 7] reported that treatment with okadaic acid, a potent ser/thr protein phosphatase inhibitor, also results in inefficient nuclear retention of agonist-bound GR and the cytoplasmic "trapping" of GR in a form that is unable to "recycle".

  • The agonist-bound form represents the normal activated state, while the antagonist-bound form is considered the inactive conformation.

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