Example sentences for: adenomatous

How can you use “adenomatous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Dsh in turn inhibits glycogen synthase kinase (GSK)-3β in the β-catenin destruction complex, which mainly consists of Axin, GSK-3β, adenomatous polyposis coli (APC) and β-catenin.

  • Dr. Miller states that there is no established treatment for adenomatous polyps.

  • The Min /+ model has received great favour because it contains a mutation in the Apc gene, which is homologous to the human adenomatous polyposis coli (APC) gene [ 23 ] . Defects in the APC tumour suppressor gene are thought to play a role in greater than 70% of all colorectal cancers and is responsible for inherited syndromes of polyposis (FAP and Gardner's) [ 24 25 ] . Furthermore, in humans the majority of colorectal cancers arise from adenomatous polyps [ 26 ] .

  • They also raise into question the efficacy of aspirin as a chemotherapeutic for colon cancer, and perhaps more specifically, familial adenomatous polyposis.

  • This is evident when one evaluates the concentrations required to achieve anticancer, cytoprotective actions in vitro [ 19 21 25 26 27 ] . More recently in the Apc minmouse model of familial adenomatous polyposis, a condition with a massive induction of polyps in the gastrointestinal tract, green tea extracts reduced polyp load and potentiated the effects of sulindac, a cyclo-oxygenase inhibitor used to treat gastrointestinal cancer [ 32 ] . This further affirms the potential of this strategy in managing disorders characterized by epithelial cell death and transformation.

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