Words similar to adenocarcinomas
Example sentences for: adenocarcinomas
How can you use “adenocarcinomas” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the same two-dimensional view, we plotted one dataset of 86 profiles from lung adenocarcinomas and another dataset of 45 profiles from glioblastomas and astrocytomas, generated from previous global gene-expression studies [ 5 6 ] . Figure 1shows this principal components analysis (PCA) plot of the gene-expression profiles from cell cultures, xenografts, and human lung and brain tumors.
In order to produce such a model for studying the effects of Pten mutations in breast cancer, we have crossed Wnt-1 TG mice to mice heterozygous for Pten . Mice transgenic for MMTV- Wnt-1 and heterozygous for Pten developed mammary adenocarcinomas much earlier than mice carrying either lesion alone.
These observations differ from a recent report that one of the other two Pten +/- lines develops fibroadenomas and adenocarcinomas in the mammary tissue after 7 months of age [ 26].
Data presented here suggest that clinical decisions regarding the use of these agents in patients with lung adenocarcinomas might be improved in the future by pre-treatment mutational profiling of both EGFR and KRAS . These findings warrant validation in large prospective trials using standardized mutation detection techniques.
We identified 60 lung adenocarcinomas from individual patients with tumors shown to be sensitive or refractory to single-agent gefitinib or erlotinib and evaluated these tumors for mutations in EGFR and KRAS . Collectively, nine of 38 (24%) tumors refractory to either kinase inhibitor had KRAS mutations, while zero of 21 (0%) drug-sensitive tumors had such mutations ( p = 0.02) (Table 1).
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